DNLI vs JPM Stock Comparison
JPM currently leads DNLI in this stock comparison, with AIQ scores of 53 vs 41. The clearest difference is quality.
What is the main difference between DNLI and JPM?
JPM leads the current stock comparison as JPMorgan Chase & Co., with the clearest separation coming from quality and the broader AIQ evidence mix.
AlgovestIQ AIQ Comparison
Denali Therapeutics Inc. vs JPMorgan Chase & Co.
JPM leads
JPM leads by 12 AIQ points, primarily on Quality and Momentum, and the lead has widened from 6 points over 30 sessions. Wall Street currently favors DNLI on target upside.
Competitive: 4 of 6 evidence groups support JPM, its lead is widening, and its current signal state is conflicted.
Denali Therapeutics Inc.
JPMorgan Chase & Co.
The Algovestiq AIQ Score currently favors JPM over DNLI, 53 versus 41 as of Oct 31, 2026. JPM's advantage is driven primarily by stronger quality and momentum. JPM also shows the stronger technical structure relative to its 50-day moving average, though analyst target upside currently favors DNLI. 4 of 6 covered evidence groups favor JPM today, and the comparison is rated Competitive on stability: the leader is throwing conflicting signals. JPM lead: Strengthening — the AIQ differential moved from 6 to 12 points over 30 sessions.
Compare Denali Therapeutics Inc. and JPMorgan Chase & Co. across the Algovestiq AIQ Score, valuation, quality, momentum, risk, technicals and analyst expectations.
Performance over time
Total return with distributions reinvested, from daily closes.
Total return comparison
Growth of $10,000, distributions reinvested
Split-adjusted closes; each distribution is reinvested at the close on its ex-dividend date. Taxes and trading costs are not modeled.
Compare DNLI and JPM against another ticker
Open a multi-ticker workspace without changing this focused pair page.
AIQ Factor Divergence
Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.
- Quality30 vs 46JPM +16
- Momentum46 vs 61JPM +15
- Value34 vs 44JPM +10
- Risk Resilience67 vs 69Even
4 of 6 evidence groups favor JPM. JPM’s edge is concentrated in quality and momentum.
What changed since the last close
Latest scored session 2026-10-28, compared against the prior scored session 2026-10-27.
Largest factor move: Momentum +3
No signal started or stopped since the prior session; its 5 active signals are unchanged.
Largest factor move: Momentum +2
New signals
- BB Upper Band Breach — bearish, volatility, short horizon
JPM's lead was unchanged in the latest session.
Deeper signal detail for each name lives on its own signals page — DNLI and JPM both carry a full feed there.
The central trade-off
JPM (JPMorgan Chase & Co.): the stronger current systematic profile, led by quality and momentum.
DNLI (Denali Therapeutics Inc.): the counter-case, on analyst expectations — but at materially higher volatility, 41.6% against 13%.
The AIQ Score and Wall Street therefore point in different directions on this pair.
Which one fits your objective
The same two names rank differently depending on what you are optimizing for. All six reads are shown at once — none of them is hidden behind a toggle.
Balanced
JPMJPM on the overall AIQ Score, which weights Quality and Value most heavily.
Growth
DNLIDNLI on combined revenue and EPS growth.
Value
JPMJPM on the peer-relative Value factor, by 10 points.
Momentum
JPMJPM on the Momentum factor, by 15 points.
Lower downside
JPMJPM carries the lower 1-month annualized volatility.
Analyst upside
DNLIDNLI on implied upside to the consensus price target.
AIQ vs Wall Street
The model and the Street disagree here: AIQ favors JPM, analyst targets favor DNLI. That disagreement is the most useful thing on this page.
| Measure | DNLI | JPM | Note |
|---|---|---|---|
| Implied upside to target | +71.6% | +10.7% | DNLI has more room |
| Target dispersion | +55.4% | +32.2% | Lower is tighter analyst agreement |
| Consensus | Buy | Buy | Context, not a primary driver |
| Analysts covering | 6 | 11 | Higher coverage generally improves confidence |
The two are measuring different things. The AIQ Score reads current fundamentals, valuation, trend and risk; analyst targets price forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something already priced in — it is worth resolving before acting on either.
Analyst targets are expectations, not predictions. Dispersion matters as much as the midpoint.
AIQ Agreement Matrix
4 of 6 covered evidence groups favor JPM. A wide gap backed by one group is a weaker case than a narrow gap backed by five.
| Evidence group | Favors | Reading |
|---|---|---|
| AIQ Score | JPM | 41 vs 53 |
| Fundamentals | JPMon balance | EPS growth 1.4% vs -27.6%; TTM ROE -55.3% vs 17.9%; gross margin -61% vs 63.2%; operating margin -150.6% vs 28.2% — JPM takes 3 of 4 decided legs, not all of them |
| Valuation | JPM | Value 34 vs 44 |
| Technicals | JPM | Price vs 50-day -9.3% vs -2%; vs 200-day -9.1% vs 5.2% |
| Risk Resilience | Even | Risk Resilience 67 vs 69 |
| Analyst expectations | DNLI | Target upside 71.6% vs 10.7% |
✓ agrees with the overall verdict · ✕ points the other way. Groups marked “not covered” lack data on one or both of DNLI and JPM and are excluded from the count.
AIQ Decision Stability
The two are close enough that your objective, not the score, should decide.
- The AIQ gap is wide at 12 points. (supports the conclusion holding)
- The leader's advantage has been widening. (supports the conclusion holding)
- The leader is throwing conflicting signals. (argues the conclusion is provisional)
Stability combines the score gap, how broadly the evidence agrees, how steady the lead has been across daily snapshots, the current signal state on both names, and analyst dispersion on JPM.
How the comparison changed
120 daily snapshots · Jun 29 – Oct 28JPM lead: Strengthening — the AIQ differential moved from 6 to 12 points over 30 sessions.
- Today
- JPM +12
- 41 vs 53
- 7 sessions ago
- JPM +13
- 37 vs 50
- 30 sessions ago
- JPM +6
- 38 vs 44
- 90 sessions ago
- JPM +8
- 44 vs 52
The lead has not changed hands in this window.
AIQ Signal Divergence
Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.
1 bullish / 2 bearish / 2 neutral, conflicted
Only DNLI
- Bollinger Band Squeeze — neutral, volatility, short horizon
- Death Cross Active — bearish, trend, long horizon (1.61%)
- ATR Expansion - Breakout Mode — neutral, volatility, short horizon (4.02%)
- Downtrend Structure Active — bearish, trend, long horizon
2 bullish / 1 bearish, conflicted
Only JPM
- Golden Cross Active — bullish, trend, long horizon (6.57%)
- BB Upper Band Breach — bearish, volatility, short horizon
Both carry 1 more signal that do not separate them: MACD Bullish Crossover.
JPM leads the comparison while carrying a conflicted signal state, which is one reason the stability rating is not higher.
Price vs model alignment
Whether the latest session's price move confirms what the model did over the same session, or contradicts it.
Price is down while the AIQ Score moved up 1 points over the same session — price and model disagree (price -1.97%, AIQ +1 points).
Price is down while the AIQ Score moved up 1 points over the same session — price and model disagree (price -1.9%, AIQ +1 points).
What would flip this result
A state, not a forecast. These are the specific, observable changes that would reverse the verdict — not a price prediction.
- 1DNLI closes the Quality gap — currently 16 points behind, the largest single contributor to JPM's edge.
- 2DNLI's Death Cross Active resolves — a bearish trend rule currently active against it.
- 3JPM's conflicting signal state resolves bearish — it currently carries 2 bullish and 1 bearish rules at once.
- 4A regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.
The full evidence
Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.
Fundamentals
JPM leads on balance| Metric | DNLI | JPM |
|---|---|---|
| Revenue growth (YoY) | 0% | -7.6% |
| EPS growth (YoY) | 1.4% | -27.6% |
| Gross margin | -61% | 63.2% |
| Operating margin | -150.6% | 28.2% |
| Return on equity (TTM) | -55.3% | 17.9% |
| Debt to equity | 0.03 | 3.32 |
Performance
Split across windows| Metric | DNLI | JPM |
|---|---|---|
| 1 week (5 sessions) | 3.3% | 1.2% |
| 1 month (20 sessions) | -6.7% | 2.6% |
| 3 months (63 sessions) | -20.8% | -3.3% |
| 6 months (126 sessions) | 3.7% | 9.7% |
| Year to date | 16.8% | 5.3% |
| 1 year (252 sessions) | 20.9% | 12.9% |
Technicals
JPM has the stronger structure| Metric | DNLI | JPM |
|---|---|---|
| RSI (14) | 54.9 | 60.9 |
| ADX (14) | 27.3 | 15 |
| Price vs 50-day | -9.3% | -2% |
| Price vs 200-day | -9.1% | 5.2% |
| Volatility (1M, annualized) | 41.6% | 13% |
Risk
Split| Metric | DNLI | JPM |
|---|---|---|
| Beta | 1.54 | 0.73 |
| Sharpe ratio | 0.44 | 0.41 |
| Sortino ratio | 0.67 | 0.56 |
| Max drawdown | -35.3% | -15.5% |
| Current drawdown | -29.1% | -7.1% |
| Annualized volatility | 55.3% | 22% |
| Value at risk (95%) | -5% | -2.4% |
Straight answers
Each answer is regenerated from the current snapshot, not written once and left to age.
Which is better, DNLI or JPM?
On the Algovestiq AIQ Score, JPM is the stronger of the two as of Oct 31, 2026, scoring 53 against DNLI's 41. The edge comes from quality and momentum. This is a systematic score, not a recommendation: it ranks the two on the same evidence, it does not know your holding period or tax position.
Is DNLI or JPM the better buy right now?
JPM carries the stronger systematic profile as of Oct 31, 2026, and the comparison is rated Competitive — 4 of 6 covered evidence groups agree. A Competitive rating means the two are close enough that your objective, not the score, should decide.
Why does the AIQ Score favor JPM over DNLI?
The composite weights Quality, Value, Momentum and Risk Resilience. JPM leads Quality by 16 points; JPM leads Momentum by 15 points; JPM leads Value by 10 points. Where the two split, the factor with the larger weight carries the result.
Which has more analyst upside, DNLI or JPM?
Analyst price targets imply +71.6% upside for DNLI and +10.7% for JPM, so the Street currently favors DNLI. That points the opposite way to the AIQ Score, which favors JPM. The two are measuring different things: the model reads current fundamentals, valuation, trend and risk; the Street is pricing forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something the analysts have already priced — it is the single most useful row on this page to investigate. Analyst targets are expectations, not predictions, and dispersion matters as much as the midpoint.
Which is better value, DNLI or JPM?
JPM is the better-valued of the two on the peer-relative Value factor. JPM on the peer-relative Value factor, by 10 points. The Value factor reads valuation relative to sector peers and to the company's own fundamental quality, so it is not the same as simply having the lower multiple.
Which has stronger growth, DNLI or JPM?
DNLI on combined revenue and EPS growth. Growth here is measured on reported revenue and earnings, not on forward estimates — it describes what the businesses have delivered, not what the Street expects next.
Which has stronger momentum, DNLI or JPM?
JPM on the Momentum factor, by 15 points. Momentum is one of the four weighted factors in the AIQ composite. It has documented persistence over three- to twelve-month horizons, which makes it a timing input rather than a reason to hold something indefinitely.
Which is riskier, DNLI or JPM?
JPM is the more resilient of the two, so the other name carries the higher downside risk. JPM carries the lower 1-month annualized volatility. Risk Resilience is a weighted factor in the composite; position sizing usually responds to it more usefully than the buy/avoid decision does.
Is DNLI more profitable than JPM?
JPM leads on the comparable margin measures — gross margin -61% vs 63.2%; operating margin -150.6% vs 28.2%; ttm roe -55.3% vs 17.9%.
Is JPM's lead over DNLI getting stronger or weaker?
JPM lead: Strengthening — the AIQ differential moved from 6 to 12 points over 30 sessions. This is measured from 120 daily comparison snapshots between 2026-06-29 and 2026-10-28. The lead has not changed hands in that window.
What would change the DNLI vs JPM verdict?
The result is a state, not a forecast, so it changes when the underlying evidence changes. Concretely: DNLI closes the Quality gap — currently 16 points behind, the largest single contributor to JPM's edge; DNLI's Death Cross Active resolves — a bearish trend rule currently active against it; JPM's conflicting signal state resolves bearish — it currently carries 2 bullish and 1 bearish rules at once; a regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.
What do the current signals say about DNLI and JPM?
DNLI: 1 bullish / 2 bearish / 2 neutral, conflicted. JPM: 2 bullish / 1 bearish, conflicted. A conflicted state means bullish and bearish rules are active on the same name at once — the technical evidence is not pointing one way, and a decision taken on it carries more timing risk. The most decision-relevant rule on DNLI is Death Cross Active (bearish, long horizon). On JPM it is Golden Cross Active (bullish, long horizon).
Compare DNLI and JPM with others
Continue your research
This page answers which of the two. These answer the questions on either side of it.
How this comparison is scored
The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.
The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.
How to use side-by-side comparison →This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.