SPY vs XBI: Performance, Holdings, Fees & Risk

SPY and XBI are ETFs, but they can differ materially in exposure, yield, fees and risk. SPY is State Street SPDR S&P 500 ETF, while XBI is State Street SPDR S&P Biotech ETF. SPY is broader by holdings count, with 505 positions versus 156 for XBI. SPY is more concentrated at the top, based on top-10 holdings weight. Current AlgovestIQ evidence has SPY ahead on AIQ Score, 65 versus 59.

Market data as of Oct 31, 2026 market close· Fund characteristics as of Oct 31, 2026
SPY
SPDR
vs
XBI
SPDR
SPY
State Street SPDR S&P 500 ETF
Issuer
SPDR
Inception
1993-01-22
XBI
State Street SPDR S&P Biotech ETF
Issuer
SPDR
Inception
2006-01-31

What is the main difference between SPY and XBI?

XBI puts 99% of its assets in Healthcare, while SPY spreads across 11 sectors with none above 39%.

Expense ratio
SPY
0.09%
XBI
0.35%
Lower annual fund costSPY
Holdings
SPY
505
XBI
156
Broader reported basketSPY
1Y return
SPY
+14%
XBI
+45.3%
Trailing performanceXBI
Annualized volatility
SPY
12.7%
XBI
29.1%
Lower realized volatilitySPY
MetricSPYXBI
Fund
Expense ratio0.09%0.35%
Holdings505156
Top-10 concentration38.2%15.9%
Distribution yieldTrailing 12 months0.98%0.35%
Average volume43,747,1509,003,461
Performance
1Y return+14%+45.3%
YTD return+13.3%+29.2%
5Y annualized returnTotal return, distributions reinvested+12.4%+4.1%
Risk
Annualized volatility12.7%29.1%
Max drawdown (1Y)-9.1%-14.9%
Max drawdown (5Y)Total return, distributions reinvested-24.5%-53.2%
Beta1.001.08
Sharpe ratio0.681.19
Sortino ratio1.042.04
AlgovestIQ
AIQ Score65/10059/100
AIQ Edge Score9/107/10
Momentum59/10073/100
Risk Resilience87/10055/100

AlgovestIQ AIQ Comparison

State Street SPDR S&P 500 ETF vs State Street SPDR S&P Biotech ETF

Data as of Oct 31, 2026· market close· Coverage 64/66 fields· High confidence
AIQ VerdictFragileAIQ Comparison Conviction 4/10

SPY leads

SPY leads by 6 AIQ points, primarily on Risk Resilience and Quality, but the lead has narrowed from 15 points over 30 sessions.

Fragile: 2 of 4 evidence groups support SPY, its lead is narrowing, and its current signal state is conflicted.

Evidence agreement: 2 of 4Comparison trend: Weakening
SPY

State Street SPDR S&P 500 ETF

Leads
AIQ Score
65/100
AIQ Edge Score
9/10
XBI

State Street SPDR S&P Biotech ETF

AIQ Score
59/100
AIQ Edge Score
7/10

The Algovestiq AIQ Score currently favors SPY over XBI, 65 versus 59 as of Oct 31, 2026. SPY's advantage is driven primarily by stronger risk resilience and quality, while XBI holds the stronger momentum profile. SPY also shows the weaker technical structure relative to its 50-day moving average. 2 of 4 covered evidence groups favor SPY today, and the comparison is rated Fragile on stability: only 2 of 4 covered evidence groups agree. SPY lead: Weakening — the AIQ differential moved from 15 to 6 points over 30 sessions.

Compare State Street SPDR S&P 500 ETF and State Street SPDR S&P Biotech ETF across performance, expense ratio, dividend yield, drawdown, volatility and the Algovestiq AIQ Score.

SPY vs XBI: which fits what

Each row is settled by a single measure. Where the gap is too small to matter it reads Similar, and no row decides the comparison as a whole.

If you wantSPYXBIFits
Lower costExpense ratio0.09%0.35%SPY
Broader diversificationNumber of holdings505156SPY
Lower concentrationWeight of the 10 largest holdings38.2%15.9%XBI
Higher incomeTrailing 12-month distribution yield0.98%0.35%SPY
Smaller drawdownsMax drawdown, 5 years-24.5%-53.2%SPY
Lower volatilityAnnualized volatility, 1 year12.7%29.1%SPY

Similar means the gap is within 0.01 percentage points of expense ratio, 25% more holdings, 3 points of top-10 weight, 0.2 points of yield, 2 points of drawdown or 1 point of volatility. Past drawdowns and volatility describe the funds’ history, not their future.

Currently unavailable

Performance over time

Total return with distributions reinvested, from daily closes for both ETFs.

SPY
+79.5%
XBI
+22.3%

Total return comparison

Growth of $10,000, distributions reinvested

SPY $17,952 · XBI $12,230

Split-adjusted closes; each distribution is reinvested at the close on its ex-dividend date. Taxes and trading costs are not modeled.

Compare SPY and XBI against another ticker

Open a multi-ticker workspace without changing this focused pair page.

Basic: 2 symbols·Explorer: 3 symbols·Pro and Premium: 5 symbols·Your limit: 2

AIQ Factor Divergence

Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.

SPY advantage
0
XBI advantage
  • Risk Resilience87 vs 55
    SPY +32
  • Quality83 vs 64
    SPY +19
  • Momentum59 vs 73
    XBI +14
  • Value41 vs 45
    XBI +4

2 of 4 evidence groups favor SPY. SPY’s edge is concentrated in risk resilience and quality; XBI keeps a meaningful momentum edge.

What changed since the last close

Latest scored session 2026-10-30, compared against the prior scored session 2026-10-29.

SPY0 AIQ

Largest factor move: Quality -1, not enough on its own to move the overall score.

No signal started or stopped since the prior session; its 6 active signals are unchanged.

XBI-1 AIQ

Largest factor move: Value -3

No signal started or stopped since the prior session; its 3 active signals are unchanged.

SPY's lead widened by 1 AIQ point in the latest session.

Deeper signal detail for each name lives on its own signals page — SPY and XBI both carry a full feed there.

The central trade-off

SPY (State Street SPDR S&P 500 ETF): the stronger current systematic profile, led by risk resilience and quality.

XBI (State Street SPDR S&P Biotech ETF): the counter-case, on momentum, value, valuation — but at materially higher volatility, 34.4% against 10%.

Fund facts, side by side

Two funds tracking overlapping universes are separated by cost and risk far more than by holdings. Those lead here.

MeasureSPYXBIWhy it matters
Expense ratio0.09%0.35%Lower is better — it compounds against you every year you hold.
Holdings505156More holdings means broader diversification, not better returns.
Average volume43,747,1509,003,461Liquidity — matters most if you trade size.
Annualized volatility12.7%29.1%Lower is a steadier ride for the same exposure.
Max drawdown (1Y)-9.1%-14.9%The worst peak-to-trough loss over the past year.
Sharpe ratio0.681.19Return per unit of risk. Higher is better.
Beta1.001.08Sensitivity to the broad market. Neither direction is better — it depends on the role in your portfolio.

Where the exposure actually sits

Sector exposure for each fund, ordered by the size of the difference.

Healthcare9.8% vs 99.3%
Financial Services11.8% vs 0.7%
Technology38.6% vs 0.0%
Consumer Cyclical9.0% vs 0.0%
Communication Services8.9% vs 0.0%
Industrials8.0% vs 0.0%
Consumer Defensive4.8% vs 0.0%
Energy3.7% vs 0.0%
SPYXBI

How much of the same holdings they own

SPY and XBI share 1.75% of their weighted exposure across 8 common holdings.

496 holdings are unique to SPY, and 146 holdings are unique to XBI. Owning both is genuinely additive — most of the capital sits in different securities.

SPY is the more concentrated of the two: its ten largest positions are 38.17% of the fund, against 15.94% for XBI (505 holdings vs 156). Concentration cuts both ways — it is what drives outperformance when the top names work, and what makes the drawdown deeper when they do not.

Largest shared positions

HoldingSPYXBIShared
ABBVABBVIE INC0.69%1.09%0.69%
AMGNAMGEN INC0.32%1.09%0.32%
GILDGILEAD SCIENCES INC0.28%1.15%0.28%
VRTXVERTEX PHARMACEUTICALS INC0.2%1.14%0.2%
REGNREGENERON PHARMACEUTICALS0.12%1.27%0.12%
MRNAMODERNA INC0.07%2.87%0.07%
BIIBBIOGEN INC0.05%1.07%0.05%
INCYINCYTE CORP0.03%1.13%0.03%

Shared weight is the lower of the two positions — the portion of capital both funds genuinely have in the same security.

What SPY adds that XBI doesn’t

HoldingSPYXBI
NVDANVIDIA CORP8.08%Not held
AAPLAPPLE INC7.33%Not held
MSFTMICROSOFT CORP5.59%Not held
AMZNAMAZON.COM INC3.77%Not held
GOOGLALPHABET INC CL A2.98%Not held
AVGOBROADCOM INC2.61%Not held

What XBI adds that SPY doesn’t

HoldingXBISPY
MRNAMODERNA INC2.87%0.07%
TWSTTWIST BIOSCIENCE CORP1.81%Not held
HALOHALOZYME THERAPEUTICS INC1.47%Not held
NTRANATERA INC1.46%Not held
KYMRKYMERA THERAPEUTICS INC1.45%Not held
TVTXTRAVERE THERAPEUTICS INC1.4%Not held

Each list is a fund’s largest positions by weight that the other fund does not hold, or holds at less than half the weight.

SPY vs XBI: five-year payout growth

XBI grew its split-adjusted payout faster over 2020-2025 — 9.61% a year against SPY's 5.05%. XBI: The payout jumped 704.4% in 2024, a single step rather than steady compounding - often an index or mandate change. XBI: A single payment in an endpoint year was 10.6x the fund's median payment, so one distribution carries much of the result.

Dividend metricSPYXBI
5Y payout CAGR5.05%9.61%
2020 annual payout$5.691$0.282
2025 annual payout$7.281$0.446
Peer rank#95 of 138#59 of 138

Split-adjusted annual distributions, 2020–2025. Research as of Sep 19, 2026. Yield and expense ratio above are current values, not part of this window.

AIQ Agreement Matrix

2 of 4 covered evidence groups favor SPY. A wide gap backed by one group is a weaker case than a narrow gap backed by five.

Evidence groupFavorsReading
AIQ ScoreSPY65 vs 59
FundamentalsNot coveredNot covered
ValuationXBIValue 41 vs 45
TechnicalsXBIPrice vs 50-day -1.6% vs -0.6%; vs 200-day 6.1% vs 11.5%
Risk ResilienceSPYRisk Resilience 87 vs 55
Analyst expectationsNot coveredNot covered

✓ agrees with the overall verdict · ✕ points the other way. Groups marked “not covered” lack data on one or both of SPY and XBI and are excluded from the count.

AIQ Decision Stability

Fragile

The conclusion is sensitive to small changes. Treat the lead as provisional and watch the flip conditions below.

  • The AIQ gap is moderate at 6 points.
  • Only 2 of 4 covered evidence groups agree. (argues the conclusion is provisional)
  • The leader's advantage has been narrowing. (argues the conclusion is provisional)
  • The leader is throwing conflicting signals. (argues the conclusion is provisional)

Stability combines the score gap, how broadly the evidence agrees, how steady the lead has been across daily snapshots, the current signal state on both names, and analyst dispersion on SPY.

How the comparison changed

120 daily snapshots · Jul 1 – Oct 30

SPY lead: Weakening — the AIQ differential moved from 15 to 6 points over 30 sessions.

Jul 1SPY leads above the line · XBI leads belowOct 30
Today
SPY +6
65 vs 59
7 sessions ago
SPY +6
59 vs 53
30 sessions ago
SPY +15
68 vs 53
90 sessions ago
Level
64 vs 64

The lead changed hands 6 times in this window, most recently on Jul 31 when SPY moved ahead of XBI.

AIQ Signal Divergence

Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.

SPYConflicted

3 bullish / 1 bearish / 2 neutral, conflicted

Only SPY

  • ATR Contraction - Coiling — neutral, volatility, short horizon (0.90%)
  • EMA Ribbon Compression — neutral, trend, medium horizon
  • 52-Week High Proximity — bullish, risk, long horizon (1.1%)
  • MACD Bearish Crossover — bearish, momentum, short horizon
XBI

3 bullish / 0 bearish

Only XBI

  • MACD Bullish Crossover — bullish, momentum, short horizon

Both carry 2 more signals that do not separate them: Golden Cross Active, Uptrend Structure Active.

SPY leads the comparison while carrying a conflicted signal state, which is one reason the stability rating is not higher.

Price vs model alignment

Whether the latest session's price move confirms what the model did over the same session, or contradicts it.

SPYNo material change

Neither the price nor the AIQ Score moved enough in the latest session to confirm or contradict the other (price -1.77%, AIQ 0 points).

XBIConfirmed weakness

Price and the AIQ Score both moved down over the latest session (price -1.15%, AIQ -1 points).

What would flip this result

A state, not a forecast. These are the specific, observable changes that would reverse the verdict — not a price prediction.

  1. 1XBI closes the Risk Resilience gap — currently 32 points behind, the largest single contributor to SPY's edge.
  2. 2XBI generates a confirmed bullish trend signal it does not currently carry, such as EMA Ribbon Expansion Bullish.
  3. 3SPY's conflicting signal state resolves bearish — it currently carries 3 bullish and 1 bearish rules at once.
  4. 4The narrowing continues — the lead has already given back 9 points over 30 sessions, and a further 6-point move would eliminate SPY's advantage entirely.

The full evidence

Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.

Performance

XBI leads 4 of 6 windows
MetricSPYXBI
1 week (5 sessions)-0.1%3.1%
1 month (20 sessions)1.3%-0.1%
3 months (63 sessions)4.1%4%
6 months (126 sessions)8.5%22.2%
Year to date13.3%29.2%
1 year (252 sessions)14%45.3%

Technicals

XBI has the stronger structure
MetricSPYXBI
RSI (14)48.660.1
ADX (14)1414.1
Price vs 50-day-1.6%-0.6%
Price vs 200-day6.1%11.5%
Volatility (1M, annualized)10%34.4%

Risk

SPY is the more resilient
MetricSPYXBI
Beta11.08
Sharpe ratio0.681.19
Sortino ratio1.042.04
Max drawdown-9.1%-14.9%
Current drawdown-0.9%-7.1%
Annualized volatility12.7%29.1%
Value at risk (95%)-1.4%-3%

Straight answers

Short answers to the questions fund investors ask about this pair, from the figures above.

What is the difference between SPY and XBI?

XBI puts 99% of its assets in Healthcare, while SPY spreads across 11 sectors with none above 39%.

How much do SPY and XBI overlap?

SPY and XBI share 1.75% of their weighted exposure across 8 common holdings. 496 holdings are unique to SPY, and 146 holdings are unique to XBI. Owning both is genuinely additive — most of the capital sits in different securities.

Which ETF is more diversified, SPY or XBI?

SPY holds more positions: 505 versus 156 for XBI.

Which has the lower expense ratio?

SPY has the lower expense ratio, 0.09% a year against 0.35% for XBI.

Which ETF has the higher distribution yield?

SPY, with a trailing 12-month distribution yield of 0.98% against 0.35% for XBI.

Which ETF has been more volatile?

XBI has been more volatile over the past year, at 29.1% annualized against 12.7% for SPY.

Which ETF has had the smaller drawdown?

SPY fell less from peak to trough over the past five years: -24.5% against -53.2% for XBI.

Compare SPY and XBI with others

Continue your research

This page answers which of the two. These answer the questions on either side of it.

How this comparison is scored

The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.

The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.

How to use side-by-side comparison →

This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.