LLY vs PFE Stock Comparison

PFE currently leads LLY in this stock comparison, with AIQ scores of 64 vs 62. The clearest difference is value, while LLY has the stronger quality profile.

Market data as of Oct 21, 2026 market close· AIQ score gap 2 points
LLY
Healthcare
vs
PFE
Healthcare
LLY
Eli Lilly and Company
Price
$1,271
Day move
-1.01%
AIQ Score
62/100
Best edge
Quality
Sector
Healthcare
PFE
Pfizer Inc.
Leads
Price
$29.85
Day move
-0.86%
AIQ Score
64/100
Best edge
Value
Sector
Healthcare

What is the main difference between LLY and PFE?

PFE leads the current stock comparison as Pfizer Inc., with the clearest separation coming from value and the broader AIQ evidence mix.

AlgovestIQ AIQ Comparison

Eli Lilly and Company vs Pfizer Inc.

Data as of Oct 21, 2026· market close· Healthcare· Coverage 66/66 fields· High confidence
AIQ VerdictFragileAIQ Comparison Conviction 2/10

PFE leads

PFE leads by 2 AIQ points, primarily on Value and Risk Resilience. Wall Street currently favors LLY on target upside.

Fragile: 2 of 6 evidence groups support PFE, and its current signal state is conflicted.

Evidence agreement: 2 of 6Comparison trend: Stable
LLY

Eli Lilly and Company

AIQ Score
62/100
AIQ Edge Score
8/10
PFE

Pfizer Inc.

Leads
AIQ Score
64/100
AIQ Edge Score
9/10

The Algovestiq AIQ Score currently favors PFE over LLY, 64 versus 62 as of Oct 21, 2026. PFE's advantage is driven primarily by stronger value and risk resilience, while LLY holds the stronger quality profile. PFE also shows the weaker technical structure relative to its 50-day moving average, though analyst target upside currently favors LLY. 2 of 6 covered evidence groups favor PFE today, and the comparison is rated Fragile on stability: the AIQ gap is narrow at 2 points. PFE lead: Stable — the AIQ differential has held near 2 points over 30 sessions.

Compare Eli Lilly and Company and Pfizer Inc. across the Algovestiq AIQ Score, valuation, quality, momentum, risk, technicals and analyst expectations.

Currently unavailable

Performance over time

Total return with distributions reinvested, from daily closes.

LLY
+451.0%
PFE
-9.0%

Total return comparison

Growth of $10,000, distributions reinvested

LLY $55,098 · PFE $9,098

Split-adjusted closes; each distribution is reinvested at the close on its ex-dividend date. Taxes and trading costs are not modeled.

Compare LLY and PFE against another ticker

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Basic: 2 symbols·Explorer: 3 symbols·Pro and Premium: 5 symbols·Your limit: 2

AIQ Factor Divergence

Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.

LLY advantage
0
PFE advantage
  • Value26 vs 67
    PFE +41
  • Quality76 vs 54
    LLY +22
  • Momentum95 vs 77
    LLY +18
  • Risk Resilience50 vs 54
    PFE +4

2 of 6 evidence groups favor PFE. PFE’s edge is concentrated in value and risk resilience; LLY keeps a meaningful quality edge.

What changed since the last close

Latest scored session 2026-10-20, compared against the prior scored session 2026-10-19.

LLY+2 AIQ

Largest factor move: Momentum +7

New signals

  • BB Upper Band Breach — bearish, volatility, short horizon
  • Keltner Channel Breakout — bullish, volatility, short horizon
  • RSI Overbought — bearish, momentum, short horizon
PFE+2 AIQ

Largest factor move: Momentum +7

New signals

  • BB Upper Band Breach — bearish, volatility, short horizon
  • Keltner Channel Breakout — bullish, volatility, short horizon

PFE's lead was unchanged in the latest session.

Deeper signal detail for each name lives on its own signals page — LLY and PFE both carry a full feed there.

The central trade-off

PFE (Pfizer Inc.): the stronger current systematic profile, led by value and risk resilience.

LLY (Eli Lilly and Company): the counter-case, on quality, momentum, fundamentals — but at materially higher volatility, 29.4% against 18.9%.

The AIQ Score and Wall Street therefore point in different directions on this pair.

Which one fits your objective

The same two names rank differently depending on what you are optimizing for. All six reads are shown at once — none of them is hidden behind a toggle.

Balanced

PFE

PFE on the overall AIQ Score, which weights Quality and Value most heavily.

Growth

LLY

LLY on combined revenue and EPS growth.

Value

PFE

PFE on the peer-relative Value factor, by 41 points.

Momentum

LLY

LLY on the Momentum factor, by 18 points.

Lower downside

PFE

PFE on Risk Resilience, by 4 points.

Analyst upside

LLY

LLY on implied upside to the consensus price target.

AIQ vs Wall Street

The model and the Street disagree here: AIQ favors PFE, analyst targets favor LLY. That disagreement is the most useful thing on this page.

MeasureLLYPFENote
Implied upside to target+4.5%-2.8%LLY has more room
Target dispersion+42.2%+24.1%Lower is tighter analyst agreement
ConsensusBuyHoldContext, not a primary driver
Analysts covering156Higher coverage generally improves confidence

The two are measuring different things. The AIQ Score reads current fundamentals, valuation, trend and risk; analyst targets price forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something already priced in — it is worth resolving before acting on either.

Analyst targets are expectations, not predictions. Dispersion matters as much as the midpoint.

Dividend growth

LLY vs PFE: regular dividend growth
Dividend metricLLYPFE
5Y dividend CAGR15.18%2.50%
2020 regular DPS$2.960$1.520
2025 regular DPS$6.000$1.720
Years increased55
No cut in windowYesYes
Cohort rank#34#315

LLY grew its split-adjusted regular dividend faster over 2020–2025 — 15.18% a year against PFE's 2.50%. Neither company reduced its regular dividend in any year of the window.

Yield and payout ratio shown elsewhere on this page are current values, not part of the study window.

Split-adjusted regular dividends per share, 2020–2025, excluding special dividends. Research as of Sep 19, 2026.

AIQ Agreement Matrix

2 of 6 covered evidence groups favor PFE. A wide gap backed by one group is a weaker case than a narrow gap backed by five.

Evidence groupFavorsReading
AIQ ScoreEven62 vs 64
FundamentalsLLYrevenue growth 16% vs 4%; EPS growth -3.9% vs -109.2%; TTM ROE 92.6% vs 4.9%; gross margin 84% vs 71.3%; operating margin 43.9% vs 25.1%
ValuationPFEValue 26 vs 67
TechnicalsLLYPrice vs 50-day 7.5% vs 6.3%; vs 200-day 18.7% vs 11.3%
Risk ResiliencePFERisk Resilience 50 vs 54
Analyst expectationsLLYTarget upside 4.5% vs -2.8%

✓ agrees with the overall verdict · ✕ points the other way. Groups marked “not covered” lack data on one or both of LLY and PFE and are excluded from the count.

AIQ Decision Stability

Fragile

The conclusion is sensitive to small changes. Treat the lead as provisional and watch the flip conditions below.

  • The AIQ gap is narrow at 2 points. (argues the conclusion is provisional)
  • Only 2 of 6 covered evidence groups agree. (argues the conclusion is provisional)
  • The leader is throwing conflicting signals. (argues the conclusion is provisional)

Stability combines the score gap, how broadly the evidence agrees, how steady the lead has been across daily snapshots, the current signal state on both names, and analyst dispersion on PFE.

How the comparison changed

120 daily snapshots · Jun 21 – Oct 20

PFE lead: Stable — the AIQ differential has held near 2 points over 30 sessions.

Jun 21LLY leads above the line · PFE leads belowOct 20
Today
PFE +2
62 vs 64
7 sessions ago
PFE +1
61 vs 62
30 sessions ago
PFE +1
63 vs 64
90 sessions ago
PFE +14
51 vs 65

The lead changed hands 3 times in this window, most recently on Sep 24 when LLY moved ahead of PFE.

AIQ Signal Divergence

Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.

LLYConflicted

6 bullish / 2 bearish, conflicted

Only LLY

  • RSI Overbought — bearish, momentum, short horizon
PFEConflicted

6 bullish / 1 bearish / 1 neutral, conflicted

Only PFE

  • Bollinger Band Squeeze — neutral, volatility, short horizon

Both carry 7 more signals that do not separate them: Golden Cross Active, BB Upper Band Breach, Keltner Channel Breakout, EMA Ribbon Expansion Bullish, 52-Week High Proximity, Uptrend Structure Active, MACD Bullish Crossover.

PFE leads the comparison while carrying a conflicted signal state, which is one reason the stability rating is not higher.

Price vs model alignment

Whether the latest session's price move confirms what the model did over the same session, or contradicts it.

LLYDivergence

Price is down while the AIQ Score moved up 2 points over the same session — price and model disagree (price -1.01%, AIQ +2 points).

PFEDivergence

Price is down while the AIQ Score moved up 2 points over the same session — price and model disagree (price -0.86%, AIQ +2 points).

What would flip this result

A state, not a forecast. These are the specific, observable changes that would reverse the verdict — not a price prediction.

  1. 1LLY closes the Value gap — currently 41 points behind, the largest single contributor to PFE's edge.
  2. 2LLY's BB Upper Band Breach resolves — a bearish volatility rule currently active against it.
  3. 3PFE's conflicting signal state resolves bearish — it currently carries 6 bullish and 1 bearish rules at once.
  4. 4A regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

The full evidence

Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.

Fundamentals

LLY leads on balance
MetricLLYPFE
Revenue growth (YoY)16%4%
EPS growth (YoY)-3.9%-109.2%
Gross margin84%71.3%
Operating margin43.9%25.1%
Return on equity (TTM)92.6%4.9%
Debt to equity1.620.74

Performance

LLY leads 5 of 6 windows
MetricLLYPFE
1 week (5 sessions)10%6.1%
1 month (20 sessions)9.7%7.8%
3 months (63 sessions)10.4%19.5%
6 months (126 sessions)42.2%10.3%
Year to date19.4%18.2%
1 year (252 sessions)56.7%22.8%

Technicals

LLY has the stronger structure
MetricLLYPFE
RSI (14)74.467.6
ADX (14)25.224.7
Price vs 50-day7.5%6.3%
Price vs 200-day18.7%11.3%
Volatility (1M, annualized)29.4%18.9%

Risk

PFE is the more resilient
MetricLLYPFE
Beta0.250.25
Sharpe ratio1.410.89
Sortino ratio2.621.49
Max drawdown-23.3%-17.1%
Current drawdown0%0%
Annualized volatility34.9%21.5%
Value at risk (95%)-2.6%-2%

Straight answers

Each answer is regenerated from the current snapshot, not written once and left to age.

Which is better, LLY or PFE?

On the Algovestiq AIQ Score, PFE is the stronger of the two as of Oct 21, 2026, scoring 64 against LLY's 62. The edge comes from value and risk resilience. LLY is not without a case — it holds the better quality profile, which matters more if that is the objective you are optimizing for. This is a systematic score, not a recommendation: it ranks the two on the same evidence, it does not know your holding period or tax position.

Is LLY or PFE the better buy right now?

PFE carries the stronger systematic profile as of Oct 21, 2026, and the comparison is rated Fragile — 2 of 6 covered evidence groups agree. A Fragile rating means the conclusion is sensitive: the AIQ gap is narrow at 2 points. Treat the lead as provisional.

Why does the AIQ Score favor PFE over LLY?

The composite weights Quality, Value, Momentum and Risk Resilience. PFE leads Value by 41 points; LLY leads Quality by 22 points; LLY leads Momentum by 18 points. Where the two split, the factor with the larger weight carries the result.

Which has more analyst upside, LLY or PFE?

Analyst price targets imply +4.5% upside for LLY and -2.8% for PFE, so the Street currently favors LLY. That points the opposite way to the AIQ Score, which favors PFE. The two are measuring different things: the model reads current fundamentals, valuation, trend and risk; the Street is pricing forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something the analysts have already priced — it is the single most useful row on this page to investigate. Analyst targets are expectations, not predictions, and dispersion matters as much as the midpoint.

Which is better value, LLY or PFE?

PFE is the better-valued of the two on the peer-relative Value factor. PFE on the peer-relative Value factor, by 41 points. The Value factor reads valuation relative to sector peers and to the company's own fundamental quality, so it is not the same as simply having the lower multiple.

Which has stronger growth, LLY or PFE?

LLY on combined revenue and EPS growth. Growth here is measured on reported revenue and earnings, not on forward estimates — it describes what the businesses have delivered, not what the Street expects next.

Which has stronger momentum, LLY or PFE?

LLY on the Momentum factor, by 18 points. Momentum is one of the four weighted factors in the AIQ composite. It has documented persistence over three- to twelve-month horizons, which makes it a timing input rather than a reason to hold something indefinitely.

Which is riskier, LLY or PFE?

PFE is the more resilient of the two, so the other name carries the higher downside risk. PFE on Risk Resilience, by 4 points. Risk Resilience is a weighted factor in the composite; position sizing usually responds to it more usefully than the buy/avoid decision does.

Is LLY more profitable than PFE?

LLY leads on the comparable margin measures — gross margin 84% vs 71.3%; operating margin 43.9% vs 25.1%; ttm roe 92.6% vs 4.9%.

Is PFE's lead over LLY getting stronger or weaker?

PFE lead: Stable — the AIQ differential has held near 2 points over 30 sessions. This is measured from 120 daily comparison snapshots between 2026-06-21 and 2026-10-20. The lead has changed hands 3 times in that window, most recently on 2026-09-24, when LLY moved ahead of PFE.

What would change the LLY vs PFE verdict?

The result is a state, not a forecast, so it changes when the underlying evidence changes. Concretely: LLY closes the Value gap — currently 41 points behind, the largest single contributor to PFE's edge; LLY's BB Upper Band Breach resolves — a bearish volatility rule currently active against it; PFE's conflicting signal state resolves bearish — it currently carries 6 bullish and 1 bearish rules at once; a regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

What do the current signals say about LLY and PFE?

LLY: 6 bullish / 2 bearish, conflicted. PFE: 6 bullish / 1 bearish / 1 neutral, conflicted. A conflicted state means bullish and bearish rules are active on the same name at once — the technical evidence is not pointing one way, and a decision taken on it carries more timing risk. The most decision-relevant rule on LLY is Golden Cross Active (bullish, long horizon). On PFE it is Golden Cross Active (bullish, long horizon).

Compare LLY and PFE with others

Continue your research

This page answers which of the two. These answer the questions on either side of it.

How this comparison is scored

The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.

The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.

How to use side-by-side comparison →

This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.