ALNY vs VRNA Stock Comparison

Compare ALNY and VRNA across AIQ Score, fundamentals, valuation, momentum, risk, analyst expectations and current market evidence.

Market data as of Sep 11, 2026 market close· AIQ score gap 13 points
ALNY
Healthcare
vs
VRNA
Healthcare
ALNY
Alnylam Pharmaceuticals, Inc.
Leads
Price
$249
Day move
+0.47%
AIQ Score
56/100
Best edge
Quality
Sector
Healthcare
VRNA
Verona Pharma plc
Price
$107
Day move
-
AIQ Score
43/100
Best edge
Risk Resilience
Sector
Healthcare

What is the main difference between ALNY and VRNA?

ALNY leads the current stock comparison as Alnylam Pharmaceuticals, Inc., with the clearest separation coming from quality and the broader AIQ evidence mix.

AlgovestIQ AIQ Comparison

Alnylam Pharmaceuticals, Inc. vs Verona Pharma plc

Data as of Sep 11, 2026· market close· Healthcare· Coverage 53/66 fields· Moderate confidence
AIQ VerdictFragileAIQ Comparison Conviction 5/10

ALNY leads

ALNY leads by 13 AIQ points, primarily on Quality, and the lead has widened from 9 points over 30 sessions.

Fragile: 2 of 5 evidence groups support ALNY, its lead is widening, and its current signal state is conflicted.

Evidence agreement: 2 of 5Comparison trend: Strengthening
ALNY

Alnylam Pharmaceuticals, Inc.

Leads
AIQ Score
56/100
AIQ Edge Score
8/10
VRNA

Verona Pharma plc

AIQ Score
43/100
AIQ Edge Score
3/10

The Algovestiq AIQ Score currently favors ALNY over VRNA, 56 versus 43 as of Sep 11, 2026. ALNY's advantage is driven primarily by stronger quality, while VRNA holds the stronger risk resilience profile. 2 of 5 covered evidence groups favor ALNY today, and the comparison is rated Fragile on stability: only 2 of 5 covered evidence groups agree. ALNY lead: Strengthening — the AIQ differential moved from 9 to 13 points over 30 sessions.

Compare Alnylam Pharmaceuticals, Inc. and Verona Pharma plc across the Algovestiq AIQ Score, valuation, quality, momentum, risk, technicals and analyst expectations.

Currently unavailable

Performance over time

Price-return comparison using available daily close history.

ALNY
+33.2%
VRNA
+1762.5%

Total return comparison

Growth of $10,000

ALNY $13,322 · VRNA $186,254

Based on available close-price history. Distribution reinvestment is not added unless already reflected in the source series.

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AIQ Factor Divergence

Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.

ALNY advantage
0
VRNA advantage
  • Quality86 vs 47
    ALNY +39
  • Risk Resilience42 vs 54
    VRNA +12
  • Value26 vs 34
    VRNA +8

2 of 5 evidence groups favor ALNY. ALNY’s edge is concentrated in quality; VRNA keeps a meaningful risk resilience edge.

What changed since the last close

Latest scored session 2026-09-10, compared against the prior scored session 2026-09-09.

ALNY-4 AIQ

Largest factor move: Momentum -16

New signals

  • Downtrend Structure Active bearish, trend, long horizon
VRNA0 AIQ

No factor moved materially.

No new signals fired.

ALNY's lead narrowed by 4 AIQ points in the latest snapshot.

Deeper signal detail for each name lives on its own signals page — ALNY and VRNA both carry a full feed there.

The central trade-off

ALNY (Alnylam Pharmaceuticals, Inc.): the stronger current systematic profile, led by quality.

VRNA (Verona Pharma plc): the counter-case, on risk resilience, value, fundamentals.

Which one fits your objective

The same two names rank differently depending on what you are optimizing for. All six reads are shown at once — none of them is hidden behind a toggle.

Balanced

ALNY

ALNY on the overall AIQ Score, which weights Quality and Value most heavily.

Growth

VRNA

VRNA on combined revenue and EPS growth.

Value

VRNA

VRNA on the peer-relative Value factor, by 8 points.

Momentum

Even

The two are level on Momentum.

Lower downside

VRNA

VRNA on Risk Resilience, by 12 points.

Analyst upside

ALNY

ALNY on implied upside to the consensus price target.

AIQ vs Wall Street

Where the systematic read and the analyst consensus line up — and where they do not.

MeasureALNYVRNANote
Implied upside to target+52.1%+0.1%ALNY has more room
Target dispersion+67.4%0%Lower is tighter analyst agreement
ConsensusBuyHoldContext, not a primary driver
Analysts covering121Higher coverage generally improves confidence

Analyst targets are expectations, not predictions. Dispersion matters as much as the midpoint.

AIQ Agreement Matrix

2 of 5 covered evidence groups favor ALNY. A wide gap backed by one group is a weaker case than a narrow gap backed by five.

Evidence groupFavorsReading
AIQ ScoreALNY56 vs 43
FundamentalsVRNAon balancerevenue growth 10.6% vs 27.3%; EPS growth -20.6% vs 166.8%; TTM ROE 93.6% vs -1.6%; gross margin 79.7% vs 95.5%; operating margin 20.8% vs 1.3% — VRNA takes 3 of 5 decided legs, not all of them
ValuationVRNAValue 26 vs 34
TechnicalsNot coveredNot covered
Risk ResilienceVRNARisk Resilience 42 vs 54
Analyst expectationsALNYTarget upside 52.1% vs 0.1%

✓ agrees with the overall verdict · ✕ points the other way. Groups marked “not covered” lack data on one or both of ALNY and VRNA and are excluded from the count.

AIQ Decision Stability

Fragile

The conclusion is sensitive to small changes. Treat the lead as provisional and watch the flip conditions below.

  • The AIQ gap is wide at 13 points. (supports the conclusion holding)
  • Only 2 of 5 covered evidence groups agree. (argues the conclusion is provisional)
  • The leader's advantage has been widening. (supports the conclusion holding)
  • The leader is throwing conflicting signals. (argues the conclusion is provisional)
  • Analyst targets on the leader are widely dispersed. (argues the conclusion is provisional)

Stability combines the score gap, how broadly the evidence agrees, how steady the lead has been across daily snapshots, the current signal state on both names, and analyst dispersion on ALNY.

How the comparison changed

119 daily snapshots · May 4 Sep 10

ALNY lead: Strengthening — the AIQ differential moved from 9 to 13 points over 30 sessions.

May 4ALNY leads above the line · VRNA leads belowSep 10
Today
ALNY +13
56 vs 43
7 sessions ago
ALNY +19
62 vs 43
30 sessions ago
ALNY +9
57 vs 48
90 sessions ago
ALNY +15
63 vs 48

The lead changed hands 3 times in this window, most recently on Jul 15 when VRNA moved ahead of ALNY.

AIQ Signal Divergence

Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.

ALNYConflicted

1 bullish / 2 bearish / 1 neutral, conflicted

  • Death Cross Active bearish, trend, long horizon (24.06%)
  • Downtrend Structure Active bearish, trend, long horizon
  • ATR Expansion - Breakout Mode neutral, volatility, short horizon (4.82%)
VRNA

No active signals

ALNY leads the comparison while carrying a conflicted signal state, which is one reason the stability rating is not higher.

Price vs model alignment

Whether the latest session's price move confirms what the model did over the same session, or contradicts it.

ALNYDivergence

Price is up while the AIQ Score moved down 4 points over the same session — price and model disagree (price +0.47%, AIQ -4 points).

What would flip this result

A state, not a forecast. These are the specific, observable changes that would reverse the verdict — not a price prediction.

  1. 1VRNA closes the Quality gap — currently 39 points behind, the largest single contributor to ALNY's edge.
  2. 2VRNA generates a confirmed bullish trend signal it does not currently carry, such as Golden Cross Active or MACD Bullish Crossover.
  3. 3ALNY's conflicting signal state resolves bearish — it currently carries 1 bullish and 2 bearish rules at once.
  4. 4A regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

The full evidence

Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.

Fundamentals

VRNA leads on balance
MetricALNYVRNA
Revenue growth (YoY)10.6%27.3%
EPS growth (YoY)-20.6%166.8%
Gross margin79.7%95.5%
Operating margin20.8%1.3%
Return on equity (TTM)93.6%-1.6%
Debt to equity0.940.88

Performance

Split across windows
MetricALNYVRNA
1 week (5 sessions)-7.4%
1 month (20 sessions)10.5%
3 months (63 sessions)-15%
6 months (126 sessions)-22.8%
Year to date-37.8%
1 year (252 sessions)-45.6%

Technicals

Split
MetricALNYVRNA
RSI (14)63.3
ADX (14)16.1
Price vs 50-day-3%
Price vs 200-day-22.2%
Volatility (1M, annualized)50.2%

Risk

VRNA is the more resilient
MetricALNYVRNA
Beta0.37
Sharpe ratio-1.262.17
Sortino ratio-1.313.11
Max drawdown-58.2%-0.4%
Current drawdown-49.6%0%
Annualized volatility46.9%2.2%
Value at risk (95%)-4.2%-0.2%

Straight answers

Each answer is regenerated from the current snapshot, not written once and left to age.

Which is better, ALNY or VRNA?

On the Algovestiq AIQ Score, ALNY is the stronger of the two as of Sep 11, 2026, scoring 56 against VRNA's 43. The edge comes from quality. VRNA is not without a case — it holds the better risk resilience profile, which matters more if that is the objective you are optimizing for. This is a systematic score, not a recommendation: it ranks the two on the same evidence, it does not know your holding period or tax position.

Is ALNY or VRNA the better buy right now?

ALNY carries the stronger systematic profile as of Sep 11, 2026, and the comparison is rated Fragile — 2 of 5 covered evidence groups agree. A Fragile rating means the conclusion is sensitive: only 2 of 5 covered evidence groups agree. Treat the lead as provisional.

Why does the AIQ Score favor ALNY over VRNA?

The composite weights Quality, Value, Momentum and Risk Resilience. ALNY leads Quality by 39 points; VRNA leads Risk Resilience by 12 points; VRNA leads Value by 8 points. Where the two split, the factor with the larger weight carries the result.

Which has more analyst upside, ALNY or VRNA?

Analyst price targets imply +52.1% upside for ALNY and +0.1% for VRNA, so the Street currently favors ALNY. The model and the Street agree here, which is a broader base of evidence than either alone. Analyst targets are expectations, not predictions, and dispersion matters as much as the midpoint.

Which is better value, ALNY or VRNA?

VRNA is the better-valued of the two on the peer-relative Value factor. VRNA on the peer-relative Value factor, by 8 points. The Value factor reads valuation relative to sector peers and to the company's own fundamental quality, so it is not the same as simply having the lower multiple.

Which has stronger growth, ALNY or VRNA?

VRNA on combined revenue and EPS growth. Growth here is measured on reported revenue and earnings, not on forward estimates — it describes what the businesses have delivered, not what the Street expects next.

Which has stronger momentum, ALNY or VRNA?

The two are level on Momentum. Momentum is one of the four weighted factors in the AIQ composite. It has documented persistence over three- to twelve-month horizons, which makes it a timing input rather than a reason to hold something indefinitely.

Which is riskier, ALNY or VRNA?

VRNA is the more resilient of the two, so the other name carries the higher downside risk. VRNA on Risk Resilience, by 12 points. Risk Resilience is a weighted factor in the composite; position sizing usually responds to it more usefully than the buy/avoid decision does.

Is ALNY more profitable than VRNA?

The profitability evidence is mixed: gross margin 79.7% vs 95.5%; operating margin 20.8% vs 1.3%; ttm roe 93.6% vs -1.6%. ALNY leads on two measures and VRNA on one measure, and there is no single profitability composite that resolves the split — which of the two reads as "more profitable" depends on whether you weight pricing power or operating leverage.

Is ALNY's lead over VRNA getting stronger or weaker?

ALNY lead: Strengthening — the AIQ differential moved from 9 to 13 points over 30 sessions. This is measured from 119 daily comparison snapshots between 2026-05-04 and 2026-09-10. The lead has changed hands 3 times in that window, most recently on 2026-07-15, when VRNA moved ahead of ALNY.

What would change the ALNY vs VRNA verdict?

The result is a state, not a forecast, so it changes when the underlying evidence changes. Concretely: VRNA closes the Quality gap — currently 39 points behind, the largest single contributor to ALNY's edge; VRNA generates a confirmed bullish trend signal it does not currently carry, such as Golden Cross Active or MACD Bullish Crossover; ALNY's conflicting signal state resolves bearish — it currently carries 1 bullish and 2 bearish rules at once; a regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

What do the current signals say about ALNY and VRNA?

ALNY: 1 bullish / 2 bearish / 1 neutral, conflicted. VRNA: No active signals. A conflicted state means bullish and bearish rules are active on the same name at once — the technical evidence is not pointing one way, and a decision taken on it carries more timing risk. The most decision-relevant rule on ALNY is Death Cross Active (bearish, long horizon).

Compare ALNY and VRNA with others

Continue your research

This page answers which of the two. These answer the questions on either side of it.

How this comparison is scored

The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.

The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.

How to use side-by-side comparison →

This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.