ALNY vs WVE Stock Comparison
Compare ALNY and WVE across AIQ Score, fundamentals, valuation, momentum, risk, analyst expectations and current market evidence.
What is the main difference between ALNY and WVE?
ALNY leads the current stock comparison as Alnylam Pharmaceuticals, Inc., with the clearest separation coming from momentum and the broader AIQ evidence mix.
AlgovestIQ AIQ Comparison
Alnylam Pharmaceuticals, Inc. vs Wave Life Sciences Ltd.
ALNY leads
ALNY leads by 16 AIQ points, primarily on Momentum and Quality. Wall Street currently favors WVE on target upside.
Fragile: 3 of 6 evidence groups support ALNY, and its current signal state is conflicted.
Alnylam Pharmaceuticals, Inc.
Wave Life Sciences Ltd.
The Algovestiq AIQ Score currently favors ALNY over WVE, 56 versus 40 as of Sep 11, 2026. ALNY's advantage is driven primarily by stronger momentum and quality, while WVE holds the stronger value profile. ALNY also shows the stronger technical structure relative to its 50-day moving average, though analyst target upside currently favors WVE. 3 of 6 covered evidence groups favor ALNY today, and the comparison is rated Fragile on stability: only 3 of 6 covered evidence groups agree. ALNY lead: Stable — the AIQ differential has held near 16 points over 30 sessions.
Compare Alnylam Pharmaceuticals, Inc. and Wave Life Sciences Ltd. across the Algovestiq AIQ Score, valuation, quality, momentum, risk, technicals and analyst expectations.
Performance over time
Price-return comparison using available daily close history.
Total return comparison
Growth of $10,000
Based on available close-price history. Distribution reinvestment is not added unless already reflected in the source series.
Compare ALNY and WVE against another ticker
Open a multi-ticker workspace without changing this focused pair page.
AIQ Factor Divergence
Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.
- Momentum63 vs 25ALNY +38
- Quality86 vs 59ALNY +27
- Value26 vs 34WVE +8
- Risk Resilience42 vs 40Even
3 of 6 evidence groups favor ALNY. ALNY’s edge is concentrated in momentum and quality; WVE keeps a meaningful value edge.
What changed since the last close
Latest scored session 2026-09-10, compared against the prior scored session 2026-09-09.
Largest factor move: Momentum -16
New signals
- Downtrend Structure Active — bearish, trend, long horizon
No factor moved materially.
No new signals fired.
ALNY's lead narrowed by 4 AIQ points in the latest snapshot.
Deeper signal detail for each name lives on its own signals page — ALNY and WVE both carry a full feed there.
The central trade-off
ALNY (Alnylam Pharmaceuticals, Inc.): the stronger current systematic profile, led by momentum and quality.
WVE (Wave Life Sciences Ltd.): the counter-case, on value, valuation, analyst expectations.
The AIQ Score and Wall Street therefore point in different directions on this pair.
Which one fits your objective
The same two names rank differently depending on what you are optimizing for. All six reads are shown at once — none of them is hidden behind a toggle.
Balanced
ALNYALNY on the overall AIQ Score, which weights Quality and Value most heavily.
Growth
ALNYALNY on combined revenue and EPS growth.
Value
WVEWVE on the peer-relative Value factor, by 8 points.
Momentum
ALNYALNY on the Momentum factor, by 38 points.
Lower downside
WVEWVE carries the lower 1-month annualized volatility.
Analyst upside
WVEWVE on implied upside to the consensus price target.
AIQ vs Wall Street
The model and the Street disagree here: AIQ favors ALNY, analyst targets favor WVE. That disagreement is the most useful thing on this page.
| Measure | ALNY | WVE | Note |
|---|---|---|---|
| Implied upside to target | +52.1% | +212.2% | WVE has more room |
| Target dispersion | +67.4% | +41.9% | Lower is tighter analyst agreement |
| Consensus | Buy | Buy | Context, not a primary driver |
| Analysts covering | 12 | 7 | Higher coverage generally improves confidence |
The two are measuring different things. The AIQ Score reads current fundamentals, valuation, trend and risk; analyst targets price forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something already priced in — it is worth resolving before acting on either.
Analyst targets are expectations, not predictions. Dispersion matters as much as the midpoint.
AIQ Agreement Matrix
3 of 6 covered evidence groups favor ALNY. A wide gap backed by one group is a weaker case than a narrow gap backed by five.
| Evidence group | Favors | Reading |
|---|---|---|
| AIQ Score | ALNY | 56 vs 40 |
| Fundamentals | ALNYon balance | revenue growth 10.6% vs -94.1%; EPS growth -20.6% vs -161.5%; TTM ROE 93.6% vs -50.1%; gross margin 79.7% vs 96.5%; operating margin 20.8% vs -3.3% — ALNY takes 4 of 5 decided legs, not all of them |
| Valuation | WVE | Value 26 vs 34 |
| Technicals | ALNY | Price vs 50-day -3% vs -17.6%; vs 200-day -22.2% vs -49.5% |
| Risk Resilience | Even | Risk Resilience 42 vs 40 |
| Analyst expectations | WVE | Target upside 52.1% vs 212.2% |
✓ agrees with the overall verdict · ✕ points the other way. Groups marked “not covered” lack data on one or both of ALNY and WVE and are excluded from the count.
AIQ Decision Stability
The conclusion is sensitive to small changes. Treat the lead as provisional and watch the flip conditions below.
- The AIQ gap is wide at 16 points. (supports the conclusion holding)
- Only 3 of 6 covered evidence groups agree. (argues the conclusion is provisional)
- The leader is throwing conflicting signals. (argues the conclusion is provisional)
- Analyst targets on the leader are widely dispersed. (argues the conclusion is provisional)
Stability combines the score gap, how broadly the evidence agrees, how steady the lead has been across daily snapshots, the current signal state on both names, and analyst dispersion on ALNY.
How the comparison changed
119 daily snapshots · May 4 – Sep 10ALNY lead: Stable — the AIQ differential has held near 16 points over 30 sessions.
- Today
- ALNY +16
- 56 vs 40
- 7 sessions ago
- ALNY +19
- 62 vs 43
- 30 sessions ago
- ALNY +14
- 57 vs 43
- 90 sessions ago
- ALNY +16
- 63 vs 47
The lead changed hands once in this window, most recently on Aug 11 when ALNY moved ahead of WVE.
AIQ Signal Divergence
Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.
1 bullish / 2 bearish / 1 neutral, conflicted
- Death Cross Active — bearish, trend, long horizon (24.06%)
- Downtrend Structure Active — bearish, trend, long horizon
- ATR Expansion - Breakout Mode — neutral, volatility, short horizon (4.82%)
0 bullish / 4 bearish / 1 neutral
- Death Cross Active — bearish, trend, long horizon (66.61%)
- 52-Week Low Proximity — bearish, risk, long horizon (0.0%)
- Downtrend Structure Active — bearish, trend, long horizon
ALNY leads the comparison while carrying a conflicted signal state, which is one reason the stability rating is not higher.
Price vs model alignment
Whether the latest session's price move confirms what the model did over the same session, or contradicts it.
Price is up while the AIQ Score moved down 4 points over the same session — price and model disagree (price +0.47%, AIQ -4 points).
Neither the price nor the AIQ Score moved enough in the latest session to confirm or contradict the other (price -1.71%, AIQ 0 points).
What would flip this result
A state, not a forecast. These are the specific, observable changes that would reverse the verdict — not a price prediction.
- 1WVE closes the Momentum gap — currently 38 points behind, the largest single contributor to ALNY's edge.
- 2WVE's Death Cross Active resolves — a bearish trend rule currently active against it.
- 3ALNY's conflicting signal state resolves bearish — it currently carries 1 bullish and 2 bearish rules at once.
- 4A regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.
The full evidence
Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.
Fundamentals
ALNY leads on balance| Metric | ALNY | WVE |
|---|---|---|
| Revenue growth (YoY) | 10.6% | -94.1% |
| EPS growth (YoY) | -20.6% | -161.5% |
| Gross margin | 79.7% | 96.5% |
| Operating margin | 20.8% | -3.3% |
| Return on equity (TTM) | 93.6% | -50.1% |
| Debt to equity | 0.94 | 0.1 |
Performance
ALNY leads 4 of 6 windows| Metric | ALNY | WVE |
|---|---|---|
| 1 week (5 sessions) | -7.4% | -4.3% |
| 1 month (20 sessions) | 10.5% | -10.9% |
| 3 months (63 sessions) | -15% | -17.5% |
| 6 months (126 sessions) | -22.8% | -66.8% |
| Year to date | -37.8% | -71.4% |
| 1 year (252 sessions) | -45.6% | -38.4% |
Technicals
ALNY has the stronger structure| Metric | ALNY | WVE |
|---|---|---|
| RSI (14) | 63.3 | 30.4 |
| ADX (14) | 16.1 | 35.6 |
| Price vs 50-day | -3% | -17.6% |
| Price vs 200-day | -22.2% | -49.5% |
| Volatility (1M, annualized) | 50.2% | 45.1% |
Risk
Split| Metric | ALNY | WVE |
|---|---|---|
| Beta | 0.37 | 1.35 |
| Sharpe ratio | -1.26 | 0.27 |
| Sortino ratio | -1.31 | 0.57 |
| Max drawdown | -58.2% | -78.1% |
| Current drawdown | -49.6% | -78.1% |
| Annualized volatility | 46.9% | 168.1% |
| Value at risk (95%) | -4.2% | -5.9% |
Straight answers
Each answer is regenerated from the current snapshot, not written once and left to age.
Which is better, ALNY or WVE?
On the Algovestiq AIQ Score, ALNY is the stronger of the two as of Sep 11, 2026, scoring 56 against WVE's 40. The edge comes from momentum and quality. WVE is not without a case — it holds the better value profile, which matters more if that is the objective you are optimizing for. This is a systematic score, not a recommendation: it ranks the two on the same evidence, it does not know your holding period or tax position.
Is ALNY or WVE the better buy right now?
ALNY carries the stronger systematic profile as of Sep 11, 2026, and the comparison is rated Fragile — 3 of 6 covered evidence groups agree. A Fragile rating means the conclusion is sensitive: only 3 of 6 covered evidence groups agree. Treat the lead as provisional.
Why does the AIQ Score favor ALNY over WVE?
The composite weights Quality, Value, Momentum and Risk Resilience. ALNY leads Momentum by 38 points; ALNY leads Quality by 27 points; WVE leads Value by 8 points. Where the two split, the factor with the larger weight carries the result.
Which has more analyst upside, ALNY or WVE?
Analyst price targets imply +52.1% upside for ALNY and +212.2% for WVE, so the Street currently favors WVE. That points the opposite way to the AIQ Score, which favors ALNY. The two are measuring different things: the model reads current fundamentals, valuation, trend and risk; the Street is pricing forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something the analysts have already priced — it is the single most useful row on this page to investigate. Analyst targets are expectations, not predictions, and dispersion matters as much as the midpoint.
Which is better value, ALNY or WVE?
WVE is the better-valued of the two on the peer-relative Value factor. WVE on the peer-relative Value factor, by 8 points. The Value factor reads valuation relative to sector peers and to the company's own fundamental quality, so it is not the same as simply having the lower multiple.
Which has stronger growth, ALNY or WVE?
ALNY on combined revenue and EPS growth. Growth here is measured on reported revenue and earnings, not on forward estimates — it describes what the businesses have delivered, not what the Street expects next.
Which has stronger momentum, ALNY or WVE?
ALNY on the Momentum factor, by 38 points. Momentum is one of the four weighted factors in the AIQ composite. It has documented persistence over three- to twelve-month horizons, which makes it a timing input rather than a reason to hold something indefinitely.
Which is riskier, ALNY or WVE?
WVE is the more resilient of the two, so the other name carries the higher downside risk. WVE carries the lower 1-month annualized volatility. Risk Resilience is a weighted factor in the composite; position sizing usually responds to it more usefully than the buy/avoid decision does.
Is ALNY more profitable than WVE?
The profitability evidence is mixed: gross margin 79.7% vs 96.5%; operating margin 20.8% vs -3.3%; ttm roe 93.6% vs -50.1%. ALNY leads on two measures and WVE on one measure, and there is no single profitability composite that resolves the split — which of the two reads as "more profitable" depends on whether you weight pricing power or operating leverage.
Is ALNY's lead over WVE getting stronger or weaker?
ALNY lead: Stable — the AIQ differential has held near 16 points over 30 sessions. This is measured from 119 daily comparison snapshots between 2026-05-04 and 2026-09-10. The lead has changed hands once in that window, most recently on 2026-08-11, when ALNY moved ahead of WVE.
What would change the ALNY vs WVE verdict?
The result is a state, not a forecast, so it changes when the underlying evidence changes. Concretely: WVE closes the Momentum gap — currently 38 points behind, the largest single contributor to ALNY's edge; WVE's Death Cross Active resolves — a bearish trend rule currently active against it; ALNY's conflicting signal state resolves bearish — it currently carries 1 bullish and 2 bearish rules at once; a regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.
What do the current signals say about ALNY and WVE?
ALNY: 1 bullish / 2 bearish / 1 neutral, conflicted. WVE: 0 bullish / 4 bearish / 1 neutral. A conflicted state means bullish and bearish rules are active on the same name at once — the technical evidence is not pointing one way, and a decision taken on it carries more timing risk. The most decision-relevant rule on ALNY is Death Cross Active (bearish, long horizon). On WVE it is Death Cross Active (bearish, long horizon).
Compare ALNY and WVE with others
Continue your research
This page answers which of the two. These answer the questions on either side of it.
How this comparison is scored
The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.
The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.
How to use side-by-side comparison →This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.