ALNY vs XNCR Stock Comparison

Compare ALNY vs XNCR on performance, valuation, growth, fundamentals, momentum and risk; the current AIQ evidence does not show a clear headline leader.

Market data as of Oct 31, 2026 market close· AIQ score gap 0 points
ALNY
Healthcare
vs
XNCR
Healthcare
ALNY
Alnylam Pharmaceuticals, Inc.
Price
$165
Day move
-5.17%
AIQ Score
53/100
Best edge
Quality
Sector
Healthcare
XNCR
Xencor, Inc.
Price
$29.82
Day move
+2.09%
AIQ Score
53/100
Best edge
Momentum
Sector
Healthcare

What is the main difference between ALNY and XNCR?

ALNY and XNCR are close on the current AIQ evidence, so the better fit depends more on objective, risk tolerance and valuation preference than on a single headline score.

AlgovestIQ AIQ Comparison

Alnylam Pharmaceuticals, Inc. vs Xencor, Inc.

Data as of Oct 31, 2026· market close· Healthcare· Coverage 66/66 fields· High confidence
AIQ VerdictFragileAIQ Comparison Conviction 1/10

ALNY and XNCR are effectively level

ALNY and XNCR are effectively level on the AIQ Score; the factor table below shows where each one holds its advantage.

Evidence agreement: 0 of 6Comparison trend: Stable
ALNY

Alnylam Pharmaceuticals, Inc.

AIQ Score
53/100
AIQ Edge Score
5/10
XNCR

Xencor, Inc.

AIQ Score
53/100
AIQ Edge Score
5/10

The Algovestiq AIQ Score does not currently separate ALNY and XNCR as of Oct 31, 2026. Both names are scored on the same 0–100 scale across Quality, Value, Momentum and Risk Resilience, and the factor table below shows where each one holds its advantage.

Compare Alnylam Pharmaceuticals, Inc. and Xencor, Inc. across the Algovestiq AIQ Score, valuation, quality, momentum, risk, technicals and analyst expectations.

Currently unavailable

Performance over time

Price return from daily closes; distributions are not included.

ALNY
+39.7%
XNCR
-26.6%

Price return comparison

Growth of $10,000, price only

ALNY $13,970 · XNCR $7,340

Split-adjusted closes only. Distributions are excluded, which understates the return of any fund or stock that pays them.

Compare ALNY and XNCR against another ticker

Open a multi-ticker workspace without changing this focused pair page.

Basic: 2 symbols·Explorer: 3 symbols·Pro and Premium: 5 symbols·Your limit: 2

AIQ Factor Divergence

Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.

ALNY advantage
0
XNCR advantage
  • Quality86 vs 48
    ALNY +38
  • Momentum50 vs 81
    XNCR +31
  • Value25 vs 34
    XNCR +9
  • Risk Resilience50 vs 55
    XNCR +5

Neither name separates cleanly on the covered dimensions.

What changed since the last close

Latest scored session 2026-10-28, compared against the prior scored session 2026-10-27.

ALNY+1 AIQ

Largest factor move: Momentum +5

No signal started or stopped since the prior session; its 4 active signals are unchanged.

XNCR0 AIQ

Largest factor move: Momentum +1, not enough on its own to move the overall score.

No signal started or stopped since the prior session; its 8 active signals are unchanged.

XNCR's lead narrowed by 1 AIQ point in the latest session.

Deeper signal detail for each name lives on its own signals page — ALNY and XNCR both carry a full feed there.

Which one fits your objective

The same two names rank differently depending on what you are optimizing for. All six reads are shown at once — none of them is hidden behind a toggle.

Balanced

Even

Neither separates on the overall score.

Growth

XNCR

XNCR on combined revenue and EPS growth.

Value

XNCR

XNCR on the peer-relative Value factor, by 9 points.

Momentum

XNCR

XNCR on the Momentum factor, by 31 points.

Lower downside

XNCR

XNCR on Risk Resilience, by 5 points.

Analyst upside

ALNY

ALNY on implied upside to the consensus price target.

AIQ vs Wall Street

Where the systematic read and the analyst consensus line up — and where they do not.

MeasureALNYXNCRNote
Implied upside to target+118.8%+15.4%ALNY has more room
Target dispersion+70.6%+75.6%Lower is tighter analyst agreement
ConsensusBuyBuyContext, not a primary driver
Analysts covering135Higher coverage generally improves confidence

Analyst targets are expectations, not predictions. Dispersion matters as much as the midpoint.

AIQ Agreement Matrix

How each independent group of evidence reads the pair.

Evidence groupFavorsReading
AIQ ScoreEven53 vs 53
FundamentalsALNYon balancerevenue growth 10.6% vs 10.3%; EPS growth -20.6% vs 83%; TTM ROE 93.6% vs -28.7%; gross margin 79.7% vs 43.3%; operating margin 20.8% vs -205.8% — ALNY takes 3 of 4 decided legs, not all of them
ValuationXNCRValue 25 vs 34
TechnicalsXNCRPrice vs 50-day -31% vs 16.3%; vs 200-day -19.2% vs 78.5%
Risk ResilienceXNCRRisk Resilience 50 vs 55
Analyst expectationsALNYTarget upside 118.8% vs 15.4%

AIQ Decision Stability

Fragile

The conclusion is sensitive to small changes. Treat the lead as provisional and watch the flip conditions below.

  • The AIQ gap is narrow at 0 points. (argues the conclusion is provisional)
  • Only 0 of 6 covered evidence groups agree. (argues the conclusion is provisional)
  • Analyst targets on the leader are widely dispersed. (argues the conclusion is provisional)

How the comparison changed

120 daily snapshots · Jun 29 – Oct 28
Jun 29ALNY leads above the line · XNCR leads belowOct 28
Today
Level
53 vs 53
7 sessions ago
ALNY +8
53 vs 45
30 sessions ago
Level
45 vs 45
90 sessions ago
ALNY +5
58 vs 53

The lead changed hands 6 times in this window, most recently on Oct 26 when XNCR moved ahead of ALNY.

AIQ Signal Divergence

Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.

ALNYConflicted

1 bullish / 2 bearish / 1 neutral, conflicted

Only ALNY

  • Death Cross Active — bearish, trend, long horizon (20.20%)
  • Downtrend Structure Active — bearish, trend, long horizon
XNCRConflicted

5 bullish / 2 bearish / 1 neutral, conflicted

Only XNCR

  • Golden Cross Active — bullish, trend, long horizon (52.65%)
  • BB Upper Band Breach — bearish, volatility, short horizon
  • Keltner Channel Breakout — bullish, volatility, short horizon
  • RSI Overbought — bearish, momentum, short horizon
  • EMA Ribbon Expansion Bullish — bullish, trend, medium horizon
  • Uptrend Structure Active — bullish, trend, long horizon

Both carry 2 more signals that do not separate them: ATR Expansion - Breakout Mode, MACD Bullish Crossover.

Price vs model alignment

Whether the latest session's price move confirms what the model did over the same session, or contradicts it.

ALNYDivergence

Price is down while the AIQ Score moved up 1 points over the same session — price and model disagree (price -5.17%, AIQ +1 points).

XNCRNo material change

Neither the price nor the AIQ Score moved enough in the latest session to confirm or contradict the other (price +2.09%, AIQ 0 points).

The full evidence

Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.

Fundamentals

ALNY leads on balance
MetricALNYXNCR
Revenue growth (YoY)10.6%10.3%
EPS growth (YoY)-20.6%83%
Gross margin79.7%43.3%
Operating margin20.8%-205.8%
Return on equity (TTM)93.6%-28.7%
Debt to equity0.940.13

Performance

XNCR leads 6 of 6 windows
MetricALNYXNCR
1 week (5 sessions)3.2%19.2%
1 month (20 sessions)-5.8%20.2%
3 months (63 sessions)4.9%39.6%
6 months (126 sessions)-22.8%148.5%
Year to date-41.6%95.9%
1 year (252 sessions)-49.9%127%

Technicals

XNCR has the stronger structure
MetricALNYXNCR
RSI (14)57.272.1
ADX (14)10.421.3
Price vs 50-day-31%16.3%
Price vs 200-day-19.2%78.5%
Volatility (1M, annualized)40.9%74.6%

Risk

XNCR is the more resilient
MetricALNYXNCR
Beta0.431.17
Sharpe ratio-1.311.42
Sortino ratio-1.392.61
Max drawdown-57.3%-42.6%
Current drawdown-51.7%0%
Annualized volatility48.2%64.1%
Value at risk (95%)-4.6%-5.5%

Straight answers

Each answer is regenerated from the current snapshot, not written once and left to age.

Which has more analyst upside, ALNY or XNCR?

Analyst price targets imply +118.8% upside for ALNY and +15.4% for XNCR, so the Street currently favors ALNY. Analyst targets are expectations, not predictions, and dispersion matters as much as the midpoint.

Which is better value, ALNY or XNCR?

XNCR is the better-valued of the two on the peer-relative Value factor. XNCR on the peer-relative Value factor, by 9 points. The Value factor reads valuation relative to sector peers and to the company's own fundamental quality, so it is not the same as simply having the lower multiple.

Which has stronger growth, ALNY or XNCR?

XNCR on combined revenue and EPS growth. Growth here is measured on reported revenue and earnings, not on forward estimates — it describes what the businesses have delivered, not what the Street expects next.

Which has stronger momentum, ALNY or XNCR?

XNCR on the Momentum factor, by 31 points. Momentum is one of the four weighted factors in the AIQ composite. It has documented persistence over three- to twelve-month horizons, which makes it a timing input rather than a reason to hold something indefinitely.

Which is riskier, ALNY or XNCR?

XNCR is the more resilient of the two, so the other name carries the higher downside risk. XNCR on Risk Resilience, by 5 points. Risk Resilience is a weighted factor in the composite; position sizing usually responds to it more usefully than the buy/avoid decision does.

Is ALNY more profitable than XNCR?

ALNY leads on the comparable margin measures — gross margin 79.7% vs 43.3%; operating margin 20.8% vs -205.8%; ttm roe 93.6% vs -28.7%.

What do the current signals say about ALNY and XNCR?

ALNY: 1 bullish / 2 bearish / 1 neutral, conflicted. XNCR: 5 bullish / 2 bearish / 1 neutral, conflicted. A conflicted state means bullish and bearish rules are active on the same name at once — the technical evidence is not pointing one way, and a decision taken on it carries more timing risk. The most decision-relevant rule on ALNY is Death Cross Active (bearish, long horizon). On XNCR it is Golden Cross Active (bullish, long horizon).

Compare ALNY and XNCR with others

Continue your research

This page answers which of the two. These answer the questions on either side of it.

How this comparison is scored

The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.

The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.

How to use side-by-side comparison →

This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.