DNLI vs DTIL Stock Comparison

Compare DNLI and DTIL across AIQ Score, fundamentals, valuation, momentum, risk, analyst expectations and current market evidence.

Market data as of Sep 11, 2026 market close· AIQ score gap 12 points
DNLI
Healthcare
vs
DTIL
Healthcare
DNLI
Denali Therapeutics Inc.
Price
$21.09
Day move
-1.45%
AIQ Score
37/100
Best edge
Risk Resilience
Sector
Healthcare
DTIL
Precision BioSciences, Inc.
Leads
Price
$7.17
Day move
-0.97%
AIQ Score
49/100
Best edge
Value
Sector
Healthcare

What is the main difference between DNLI and DTIL?

DTIL leads the current stock comparison as Precision BioSciences, Inc., with the clearest separation coming from value and the broader AIQ evidence mix.

AlgovestIQ AIQ Comparison

Denali Therapeutics Inc. vs Precision BioSciences, Inc.

Data as of Sep 11, 2026· market close· Healthcare· Coverage 66/66 fields· High confidence
AIQ VerdictCompetitiveAIQ Comparison Conviction 6/10

DTIL leads

DTIL leads by 12 AIQ points, primarily on Value and Quality.

Competitive: 4 of 6 evidence groups support DTIL, and its current signal state is conflicted.

Evidence agreement: 4 of 6Comparison trend: Stable
DNLI

Denali Therapeutics Inc.

AIQ Score
37/100
AIQ Edge Score
2/10
DTIL

Precision BioSciences, Inc.

Leads
AIQ Score
49/100
AIQ Edge Score
6/10

The Algovestiq AIQ Score currently favors DTIL over DNLI, 49 versus 37 as of Sep 11, 2026. DTIL's advantage is driven primarily by stronger value and quality, while DNLI holds the stronger risk resilience profile. DTIL also shows the stronger technical structure relative to its 50-day moving average. 4 of 6 covered evidence groups favor DTIL today, and the comparison is rated Competitive on stability: the leader is throwing conflicting signals. DTIL lead: Stable — the AIQ differential has held near 12 points over 30 sessions.

Compare Denali Therapeutics Inc. and Precision BioSciences, Inc. across the Algovestiq AIQ Score, valuation, quality, momentum, risk, technicals and analyst expectations.

Currently unavailable

Performance over time

Price-return comparison using available daily close history.

DNLI
-59.1%
DTIL
-98.1%

Total return comparison

Growth of $10,000

DNLI $4,087 · DTIL $190

Based on available close-price history. Distribution reinvestment is not added unless already reflected in the source series.

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AIQ Factor Divergence

Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.

DNLI advantage
0
DTIL advantage
  • Value34 vs 60
    DTIL +26
  • Quality30 vs 51
    DTIL +21
  • Risk Resilience70 vs 51
    DNLI +19
  • Momentum31 vs 31
    Even

4 of 6 evidence groups favor DTIL. DTIL’s edge is concentrated in value and quality; DNLI keeps a meaningful risk resilience edge.

What changed since the last close

Latest scored session 2026-09-10, compared against the prior scored session 2026-09-09.

DNLI0 AIQ

Largest factor move: Risk Resilience +1

No new signals fired.

DTIL0 AIQ

No factor moved materially.

No new signals fired.

DTIL's lead was unchanged in the latest snapshot.

Deeper signal detail for each name lives on its own signals page — DNLI and DTIL both carry a full feed there.

The central trade-off

DTIL (Precision BioSciences, Inc.): the stronger current systematic profile, led by value and quality.

DNLI (Denali Therapeutics Inc.): the counter-case, on risk resilience.

Which one fits your objective

The same two names rank differently depending on what you are optimizing for. All six reads are shown at once — none of them is hidden behind a toggle.

Balanced

DTIL

DTIL on the overall AIQ Score, which weights Quality and Value most heavily.

Growth

DNLI

DNLI on combined revenue and EPS growth.

Value

DTIL

DTIL on the peer-relative Value factor, by 26 points.

Momentum

Even

The two are level on Momentum.

Lower downside

DNLI

DNLI on Risk Resilience, by 19 points.

Analyst upside

DTIL

DTIL on implied upside to the consensus price target.

AIQ vs Wall Street

Where the systematic read and the analyst consensus line up — and where they do not.

MeasureDNLIDTILNote
Implied upside to target+55.4%+178.9%DTIL has more room
Target dispersion+54.9%0%Lower is tighter analyst agreement
ConsensusBuyBuyContext, not a primary driver
Analysts covering61Higher coverage generally improves confidence

Analyst targets are expectations, not predictions. Dispersion matters as much as the midpoint.

AIQ Agreement Matrix

4 of 6 covered evidence groups favor DTIL. A wide gap backed by one group is a weaker case than a narrow gap backed by five.

Evidence groupFavorsReading
AIQ ScoreDTIL37 vs 49
FundamentalsEvenEPS growth 1.4% vs -68%; TTM ROE -55.3% vs -91.6%; gross margin -61% vs 100%; operating margin -150.6% vs -80.8%
ValuationDTILValue 34 vs 60
TechnicalsDTILPrice vs 50-day -12.8% vs -8.5%; vs 200-day 2.4% vs 17%
Risk ResilienceDNLIRisk Resilience 70 vs 51
Analyst expectationsDTILTarget upside 55.4% vs 178.9%

✓ agrees with the overall verdict · ✕ points the other way. Groups marked “not covered” lack data on one or both of DNLI and DTIL and are excluded from the count.

AIQ Decision Stability

Competitive

The two are close enough that your objective, not the score, should decide.

  • The AIQ gap is wide at 12 points. (supports the conclusion holding)
  • The lead has been steady session to session. (supports the conclusion holding)
  • The leader is throwing conflicting signals. (argues the conclusion is provisional)

Stability combines the score gap, how broadly the evidence agrees, how steady the lead has been across daily snapshots, the current signal state on both names, and analyst dispersion on DTIL.

How the comparison changed

119 daily snapshots · May 4 Sep 10

DTIL lead: Stable — the AIQ differential has held near 12 points over 30 sessions.

May 4DNLI leads above the line · DTIL leads belowSep 10
Today
DTIL +12
37 vs 49
7 sessions ago
DTIL +15
38 vs 53
30 sessions ago
DTIL +14
47 vs 61
90 sessions ago
DTIL +12
49 vs 61

The lead has not changed hands in this window.

AIQ Signal Divergence

Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.

DNLIConflicted

2 bullish / 2 bearish / 2 neutral, conflicted

  • Golden Cross Active bullish, trend, long horizon (15.68%)
  • Bollinger Band Squeeze neutral, volatility, short horizon
  • Keltner Channel Breakdown bearish, volatility, short horizon
DTILConflicted

2 bullish / 1 bearish / 2 neutral, conflicted

  • Golden Cross Active bullish, trend, long horizon (26.60%)
  • Bollinger Band Squeeze neutral, volatility, short horizon
  • RSI Oversold - Potential Bounce bullish, momentum, short horizon

DTIL leads the comparison while carrying a conflicted signal state, which is one reason the stability rating is not higher.

Price vs model alignment

Whether the latest session's price move confirms what the model did over the same session, or contradicts it.

DNLINo material change

Neither the price nor the AIQ Score moved enough in the latest session to confirm or contradict the other (price -1.45%, AIQ 0 points).

DTILNo material change

Neither the price nor the AIQ Score moved enough in the latest session to confirm or contradict the other (price -0.97%, AIQ 0 points).

What would flip this result

A state, not a forecast. These are the specific, observable changes that would reverse the verdict — not a price prediction.

  1. 1DNLI closes the Value gap — currently 26 points behind, the largest single contributor to DTIL's edge.
  2. 2DNLI's Keltner Channel Breakdown resolves — a bearish volatility rule currently active against it.
  3. 3DTIL's conflicting signal state resolves bearish — it currently carries 2 bullish and 1 bearish rules at once.
  4. 4A regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

The full evidence

Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.

Fundamentals

Split
MetricDNLIDTIL
Revenue growth (YoY)0%-100%
EPS growth (YoY)1.4%-68%
Gross margin-61%100%
Operating margin-150.6%-80.8%
Return on equity (TTM)-55.3%-91.6%
Debt to equity0.030.62

Performance

DTIL leads 6 of 6 windows
MetricDNLIDTIL
1 week (5 sessions)-6.3%-2.8%
1 month (20 sessions)-15.3%-2.4%
3 months (63 sessions)3.8%12.2%
6 months (126 sessions)-0.7%43.1%
Year to date29.6%74%
1 year (252 sessions)39%45.7%

Technicals

DTIL has the stronger structure
MetricDNLIDTIL
RSI (14)24.415.4
ADX (14)25.816.9
Price vs 50-day-12.8%-8.5%
Price vs 200-day2.4%17%
Volatility (1M, annualized)33.9%57.2%

Risk

DNLI is the more resilient
MetricDNLIDTIL
Beta1.541.15
Sharpe ratio0.80.79
Sortino ratio1.21.32
Max drawdown-21.4%-58.5%
Current drawdown-21.4%-22%
Annualized volatility56.8%72.1%
Value at risk (95%)-5.3%-7.5%

Straight answers

Each answer is regenerated from the current snapshot, not written once and left to age.

Which is better, DNLI or DTIL?

On the Algovestiq AIQ Score, DTIL is the stronger of the two as of Sep 11, 2026, scoring 49 against DNLI's 37. The edge comes from value and quality. DNLI is not without a case — it holds the better risk resilience profile, which matters more if that is the objective you are optimizing for. This is a systematic score, not a recommendation: it ranks the two on the same evidence, it does not know your holding period or tax position.

Is DNLI or DTIL the better buy right now?

DTIL carries the stronger systematic profile as of Sep 11, 2026, and the comparison is rated Competitive — 4 of 6 covered evidence groups agree. A Competitive rating means the two are close enough that your objective, not the score, should decide.

Why does the AIQ Score favor DTIL over DNLI?

The composite weights Quality, Value, Momentum and Risk Resilience. DTIL leads Value by 26 points; DTIL leads Quality by 21 points; DNLI leads Risk Resilience by 19 points. Where the two split, the factor with the larger weight carries the result.

Which has more analyst upside, DNLI or DTIL?

Analyst price targets imply +55.4% upside for DNLI and +178.9% for DTIL, so the Street currently favors DTIL. The model and the Street agree here, which is a broader base of evidence than either alone. Analyst targets are expectations, not predictions, and dispersion matters as much as the midpoint.

Which is better value, DNLI or DTIL?

DTIL is the better-valued of the two on the peer-relative Value factor. DTIL on the peer-relative Value factor, by 26 points. The Value factor reads valuation relative to sector peers and to the company's own fundamental quality, so it is not the same as simply having the lower multiple.

Which has stronger growth, DNLI or DTIL?

DNLI on combined revenue and EPS growth. Growth here is measured on reported revenue and earnings, not on forward estimates — it describes what the businesses have delivered, not what the Street expects next.

Which has stronger momentum, DNLI or DTIL?

The two are level on Momentum. Momentum is one of the four weighted factors in the AIQ composite. It has documented persistence over three- to twelve-month horizons, which makes it a timing input rather than a reason to hold something indefinitely.

Which is riskier, DNLI or DTIL?

DNLI is the more resilient of the two, so the other name carries the higher downside risk. DNLI on Risk Resilience, by 19 points. Risk Resilience is a weighted factor in the composite; position sizing usually responds to it more usefully than the buy/avoid decision does.

Is DNLI more profitable than DTIL?

The profitability evidence is mixed: gross margin -61% vs 100%; operating margin -150.6% vs -80.8%; ttm roe -55.3% vs -91.6%. DNLI leads on one measure and DTIL on two measures, and there is no single profitability composite that resolves the split — which of the two reads as "more profitable" depends on whether you weight pricing power or operating leverage.

Is DTIL's lead over DNLI getting stronger or weaker?

DTIL lead: Stable — the AIQ differential has held near 12 points over 30 sessions. This is measured from 119 daily comparison snapshots between 2026-05-04 and 2026-09-10. The lead has not changed hands in that window.

What would change the DNLI vs DTIL verdict?

The result is a state, not a forecast, so it changes when the underlying evidence changes. Concretely: DNLI closes the Value gap — currently 26 points behind, the largest single contributor to DTIL's edge; DNLI's Keltner Channel Breakdown resolves — a bearish volatility rule currently active against it; DTIL's conflicting signal state resolves bearish — it currently carries 2 bullish and 1 bearish rules at once; a regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

What do the current signals say about DNLI and DTIL?

DNLI: 2 bullish / 2 bearish / 2 neutral, conflicted. DTIL: 2 bullish / 1 bearish / 2 neutral, conflicted. A conflicted state means bullish and bearish rules are active on the same name at once — the technical evidence is not pointing one way, and a decision taken on it carries more timing risk. The most decision-relevant rule on DNLI is Golden Cross Active (bullish, long horizon). On DTIL it is Golden Cross Active (bullish, long horizon).

Compare DNLI and DTIL with others

Continue your research

This page answers which of the two. These answer the questions on either side of it.

How this comparison is scored

The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.

The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.

How to use side-by-side comparison →

This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.