KPTI vs SNDK Stock Comparison
KPTI currently leads SNDK in this stock comparison, with AIQ scores of 67 vs 56. The clearest difference is momentum, while SNDK has the stronger risk resilience profile.
What is the main difference between KPTI and SNDK?
KPTI leads the current stock comparison as Karyopharm Therapeutics Inc., with the clearest separation coming from momentum and the broader AIQ evidence mix.
AlgovestIQ AIQ Comparison
Karyopharm Therapeutics Inc. vs Sandisk Corporation
KPTI leads
KPTI leads by 11 AIQ points, primarily on Momentum and Value, having only recently taken the lead back from SNDK.
Fragile: 3 of 6 evidence groups support KPTI, the lead recently changed hands, and its current signal state is conflicted.
Karyopharm Therapeutics Inc.
Sandisk Corporation
The Algovestiq AIQ Score currently favors KPTI over SNDK, 67 versus 56 as of Oct 31, 2026. KPTI's advantage is driven primarily by stronger momentum and value, while SNDK holds the stronger risk resilience profile. KPTI also shows the weaker technical structure relative to its 50-day moving average. 3 of 6 covered evidence groups favor KPTI today, and the comparison is rated Fragile on stability: only 3 of 6 covered evidence groups agree. KPTI lead: Reversed — SNDK led by 2 AIQ points 30 sessions ago; KPTI now leads by 11.
Compare Karyopharm Therapeutics Inc. and Sandisk Corporation across the Algovestiq AIQ Score, valuation, quality, momentum, risk, technicals and analyst expectations.
Performance over time
Price return from daily closes; distributions are not included.
Price return comparison
Growth of $10,000, price only
Split-adjusted closes only. Distributions are excluded, which understates the return of any fund or stock that pays them.
Compare KPTI and SNDK against another ticker
Open a multi-ticker workspace without changing this focused pair page.
AIQ Factor Divergence
Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.
- Momentum51 vs 20KPTI +31
- Value65 vs 50KPTI +15
- Risk Resilience32 vs 38SNDK +6
- Quality100 vs 100Even
3 of 6 evidence groups favor KPTI. KPTI’s edge is concentrated in momentum and value; SNDK keeps a meaningful risk resilience edge.
What changed since the last close
Latest scored session 2026-10-28, compared against the prior scored session 2026-10-27.
Largest factor move: Momentum +19
No signal started or stopped since the prior session; its 4 active signals are unchanged.
Largest factor move: Momentum +5
No signal started or stopped since the prior session; its 3 active signals are unchanged.
KPTI's lead widened by 3 AIQ points in the latest session.
Deeper signal detail for each name lives on its own signals page — KPTI and SNDK both carry a full feed there.
The central trade-off
KPTI (Karyopharm Therapeutics Inc.): the stronger current systematic profile, led by momentum and value.
SNDK (Sandisk Corporation): the counter-case, on risk resilience, fundamentals, technicals.
Which one fits your objective
The same two names rank differently depending on what you are optimizing for. All six reads are shown at once — none of them is hidden behind a toggle.
Balanced
KPTIKPTI on the overall AIQ Score, which weights Quality and Value most heavily.
Growth
SNDKSNDK on combined revenue and EPS growth.
Value
KPTIKPTI on the peer-relative Value factor, by 15 points.
Momentum
KPTIKPTI on the Momentum factor, by 31 points.
Lower downside
SNDKSNDK on Risk Resilience, by 6 points.
Analyst upside
KPTIKPTI on implied upside to the consensus price target.
AIQ vs Wall Street
Where the systematic read and the analyst consensus line up — and where they do not.
| Measure | KPTI | SNDK | Note |
|---|---|---|---|
| Implied upside to target | +1221.8% | +89.6% | KPTI has more room |
| Target dispersion | +148.6% | +89.3% | Lower is tighter analyst agreement |
| Consensus | Buy | Buy | Context, not a primary driver |
| Analysts covering | 3 | 14 | Higher coverage generally improves confidence |
Analyst targets are expectations, not predictions. Dispersion matters as much as the midpoint.
AIQ Agreement Matrix
3 of 6 covered evidence groups favor KPTI. A wide gap backed by one group is a weaker case than a narrow gap backed by five.
| Evidence group | Favors | Reading |
|---|---|---|
| AIQ Score | KPTI | 67 vs 56 |
| Fundamentals | SNDKon balance | revenue growth -4.7% vs 50.7%; EPS growth -127.5% vs 92.9%; TTM ROE 77.6% vs 93.1%; gross margin 95.9% vs 71.5%; operating margin -56.2% vs 61.2% — SNDK takes 4 of 5 decided legs, not all of them |
| Valuation | KPTI | Value 65 vs 50 |
| Technicals | SNDK | Price vs 50-day -47.8% vs -26.8%; vs 200-day -86.4% vs 12.3% |
| Risk Resilience | SNDK | Risk Resilience 32 vs 38 |
| Analyst expectations | KPTI | Target upside 1221.8% vs 89.6% |
✓ agrees with the overall verdict · ✕ points the other way. Groups marked “not covered” lack data on one or both of KPTI and SNDK and are excluded from the count.
AIQ Decision Stability
The conclusion is sensitive to small changes. Treat the lead as provisional and watch the flip conditions below.
- The AIQ gap is moderate at 11 points.
- Only 3 of 6 covered evidence groups agree. (argues the conclusion is provisional)
- The lead has already changed hands inside the comparison window. (argues the conclusion is provisional)
- The lead has been steady session to session. (supports the conclusion holding)
- The leader is throwing conflicting signals. (argues the conclusion is provisional)
- Analyst targets on the leader are widely dispersed. (argues the conclusion is provisional)
Stability combines the score gap, how broadly the evidence agrees, how steady the lead has been across daily snapshots, the current signal state on both names, and analyst dispersion on KPTI.
How the comparison changed
120 daily snapshots · Jun 29 – Oct 28KPTI lead: Reversed — SNDK led by 2 AIQ points 30 sessions ago; KPTI now leads by 11.
- Today
- KPTI +11
- 67 vs 56
- 7 sessions ago
- KPTI +9
- 63 vs 54
- 30 sessions ago
- SNDK +2
- 61 vs 63
- 90 sessions ago
- SNDK +6
- 65 vs 71
The lead changed hands 4 times in this window, most recently on Oct 8 when KPTI moved ahead of SNDK.
AIQ Signal Divergence
Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.
1 bullish / 2 bearish / 1 neutral, conflicted
Only KPTI
- Death Cross Active — bearish, trend, long horizon (381.47%)
- Downtrend Structure Active — bearish, trend, long horizon
- MACD Bullish Crossover — bullish, momentum, short horizon
1 bullish / 1 bearish / 1 neutral, conflicted
Only SNDK
- Golden Cross Active — bullish, trend, long horizon (25.67%)
- MACD Bearish Crossover — bearish, momentum, short horizon
Both carry 1 more signal that do not separate them: ATR Expansion - Breakout Mode.
KPTI leads the comparison while carrying a conflicted signal state, which is one reason the stability rating is not higher.
Price vs model alignment
Whether the latest session's price move confirms what the model did over the same session, or contradicts it.
Price is down while the AIQ Score moved up 5 points over the same session — price and model disagree (price -24.76%, AIQ +5 points).
Price is down while the AIQ Score moved up 2 points over the same session — price and model disagree (price -13.47%, AIQ +2 points).
What would flip this result
A state, not a forecast. These are the specific, observable changes that would reverse the verdict — not a price prediction.
- 1SNDK closes the Momentum gap — currently 31 points behind, the largest single contributor to KPTI's edge.
- 2SNDK's MACD Bearish Crossover resolves — a bearish momentum rule currently active against it.
- 3KPTI's conflicting signal state resolves bearish — it currently carries 1 bullish and 2 bearish rules at once.
- 4A regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.
The full evidence
Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.
Fundamentals
SNDK leads on balance| Metric | KPTI | SNDK |
|---|---|---|
| Revenue growth (YoY) | -4.7% | 50.7% |
| EPS growth (YoY) | -127.5% | 92.9% |
| Gross margin | 95.9% | 71.5% |
| Operating margin | -56.2% | 61.2% |
| Return on equity (TTM) | 77.6% | 93.1% |
| Debt to equity | -0.65 | 0.02 |
Performance
SNDK leads 5 of 6 windows| Metric | KPTI | SNDK |
|---|---|---|
| 1 week (5 sessions) | 50.2% | 1.9% |
| 1 month (20 sessions) | -31.8% | -19.3% |
| 3 months (63 sessions) | -88.1% | 9.8% |
| 6 months (126 sessions) | -90.1% | 32% |
| Year to date | -88.7% | 491.8% |
| 1 year (252 sessions) | -86.9% | 670% |
Technicals
SNDK has the stronger structure| Metric | KPTI | SNDK |
|---|---|---|
| RSI (14) | 61.2 | 35.5 |
| ADX (14) | 54.3 | 24.7 |
| Price vs 50-day | -47.8% | -26.8% |
| Price vs 200-day | -86.4% | 12.3% |
| Volatility (1M, annualized) | — | 66.7% |
Risk
SNDK is the more resilient| Metric | KPTI | SNDK |
|---|---|---|
| Beta | 0.48 | 4.02 |
| Sharpe ratio | -0.5 | 2.37 |
| Sortino ratio | -0.59 | 4.11 |
| Max drawdown | -97% | -56.5% |
| Current drawdown | -92.2% | -39.8% |
| Annualized volatility | 148.2% | 112.9% |
| Value at risk (95%) | -10.3% | -10.7% |
Straight answers
Each answer is regenerated from the current snapshot, not written once and left to age.
Which is better, KPTI or SNDK?
On the Algovestiq AIQ Score, KPTI is the stronger of the two as of Oct 31, 2026, scoring 67 against SNDK's 56. The edge comes from momentum and value. SNDK is not without a case — it holds the better risk resilience profile, which matters more if that is the objective you are optimizing for. This is a systematic score, not a recommendation: it ranks the two on the same evidence, it does not know your holding period or tax position.
Is KPTI or SNDK the better buy right now?
KPTI carries the stronger systematic profile as of Oct 31, 2026, and the comparison is rated Fragile — 3 of 6 covered evidence groups agree. A Fragile rating means the conclusion is sensitive: only 3 of 6 covered evidence groups agree. Treat the lead as provisional.
Why does the AIQ Score favor KPTI over SNDK?
The composite weights Quality, Value, Momentum and Risk Resilience. KPTI leads Momentum by 31 points; KPTI leads Value by 15 points; SNDK leads Risk Resilience by 6 points. Where the two split, the factor with the larger weight carries the result.
Which has more analyst upside, KPTI or SNDK?
Analyst price targets imply +1221.8% upside for KPTI and +89.6% for SNDK, so the Street currently favors KPTI. The model and the Street agree here, which is a broader base of evidence than either alone. Analyst targets are expectations, not predictions, and dispersion matters as much as the midpoint.
Which is better value, KPTI or SNDK?
KPTI is the better-valued of the two on the peer-relative Value factor. KPTI on the peer-relative Value factor, by 15 points. The Value factor reads valuation relative to sector peers and to the company's own fundamental quality, so it is not the same as simply having the lower multiple.
Which has stronger growth, KPTI or SNDK?
SNDK on combined revenue and EPS growth. Growth here is measured on reported revenue and earnings, not on forward estimates — it describes what the businesses have delivered, not what the Street expects next.
Which has stronger momentum, KPTI or SNDK?
KPTI on the Momentum factor, by 31 points. Momentum is one of the four weighted factors in the AIQ composite. It has documented persistence over three- to twelve-month horizons, which makes it a timing input rather than a reason to hold something indefinitely.
Which is riskier, KPTI or SNDK?
SNDK is the more resilient of the two, so the other name carries the higher downside risk. SNDK on Risk Resilience, by 6 points. Risk Resilience is a weighted factor in the composite; position sizing usually responds to it more usefully than the buy/avoid decision does.
Is KPTI more profitable than SNDK?
The profitability evidence is mixed: gross margin 95.9% vs 71.5%; operating margin -56.2% vs 61.2%; ttm roe 77.6% vs 93.1%. KPTI leads on one measure and SNDK on two measures, and there is no single profitability composite that resolves the split — which of the two reads as "more profitable" depends on whether you weight pricing power or operating leverage.
Is KPTI's lead over SNDK getting stronger or weaker?
KPTI lead: Reversed — SNDK led by 2 AIQ points 30 sessions ago; KPTI now leads by 11. This is measured from 120 daily comparison snapshots between 2026-06-29 and 2026-10-28. The lead has changed hands 4 times in that window, most recently on 2026-10-08, when KPTI moved ahead of SNDK.
What would change the KPTI vs SNDK verdict?
The result is a state, not a forecast, so it changes when the underlying evidence changes. Concretely: SNDK closes the Momentum gap — currently 31 points behind, the largest single contributor to KPTI's edge; SNDK's MACD Bearish Crossover resolves — a bearish momentum rule currently active against it; KPTI's conflicting signal state resolves bearish — it currently carries 1 bullish and 2 bearish rules at once; a regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.
What do the current signals say about KPTI and SNDK?
KPTI: 1 bullish / 2 bearish / 1 neutral, conflicted. SNDK: 1 bullish / 1 bearish / 1 neutral, conflicted. A conflicted state means bullish and bearish rules are active on the same name at once — the technical evidence is not pointing one way, and a decision taken on it carries more timing risk. The most decision-relevant rule on KPTI is Death Cross Active (bearish, long horizon). On SNDK it is Golden Cross Active (bullish, long horizon).
Compare KPTI and SNDK with others
Continue your research
This page answers which of the two. These answer the questions on either side of it.
How this comparison is scored
The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.
The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.
How to use side-by-side comparison →This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.