SDGR vs TEM Stock Comparison

Compare SDGR and TEM across AIQ Score, fundamentals, valuation, momentum, risk, analyst expectations and current market evidence.

Market data as of Sep 11, 2026 market close· AIQ score gap 16 points
SDGR
Technology
vs
TEM
Healthcare
SDGR
Schrödinger, Inc.
Leads
Price
$19.02
Day move
+1.17%
AIQ Score
52/100
Best edge
Quality
Sector
Technology
TEM
Tempus AI, Inc.
Price
$59.01
Day move
+0.46%
AIQ Score
36/100
Best edge
Balanced
Sector
Healthcare

What is the main difference between SDGR and TEM?

SDGR leads the current stock comparison as Schrödinger, Inc., with the clearest separation coming from quality and the broader AIQ evidence mix.

AlgovestIQ AIQ Comparison

Schrödinger, Inc. vs Tempus AI, Inc.

Data as of Sep 11, 2026· market close· Cross-sector · Technology vs Healthcare · both in AI / Data Infrastructure & Crypto Mining· Coverage 66/66 fields· High confidence
AIQ VerdictCompetitiveAIQ Comparison Conviction 7/10

SDGR leads

SDGR leads by 16 AIQ points, primarily on Quality and Value. Wall Street currently favors TEM on target upside.

Competitive: 4 of 6 evidence groups support SDGR, and its current signal state is conflicted.

Evidence agreement: 4 of 6Comparison trend: Stable
SDGR

Schrödinger, Inc.

Leads
AIQ Score
52/100
AIQ Edge Score
6/10
TEM

Tempus AI, Inc.

AIQ Score
36/100
AIQ Edge Score
2/10

The Algovestiq AIQ Score currently favors SDGR over TEM, 52 versus 36 as of Sep 11, 2026. SDGR's advantage is driven primarily by stronger quality and value. SDGR also shows the stronger technical structure relative to its 50-day moving average, though analyst target upside currently favors TEM. 4 of 6 covered evidence groups favor SDGR today, and the comparison is rated Competitive on stability: the leader is throwing conflicting signals. SDGR lead: Stable — the AIQ differential has held near 16 points over 30 sessions. SDGR leads on all four AIQ factor dimensions. Value is itself one of those four, so a sweep is not explained by valuation alone — it deserves additional scrutiny for unmodeled catalysts, expectations or event risk.

Compare Schrödinger, Inc. and Tempus AI, Inc. across the Algovestiq AIQ Score, valuation, quality, momentum, risk, technicals and analyst expectations.

Currently unavailable

Performance over time

Price-return comparison using available daily close history.

SDGR
-8.9%
TEM
+45.9%

Total return comparison

Growth of $10,000

SDGR $9,113 · TEM $14,594

Based on available close-price history. Distribution reinvestment is not added unless already reflected in the source series.

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AIQ Factor Divergence

Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.

SDGR advantage
0
TEM advantage
  • Quality51 vs 29
    SDGR +22
  • Value52 vs 35
    SDGR +17
  • Risk Resilience43 vs 28
    SDGR +15
  • Momentum57 vs 49
    SDGR +8

4 of 6 evidence groups favor SDGR. SDGR’s edge is concentrated in quality and value.

What changed since the last close

Latest scored session 2026-09-10, compared against the prior scored session 2026-09-09.

SDGR0 AIQ

Largest factor move: Momentum -1

No new signals fired.

TEM-2 AIQ

Largest factor move: Momentum -11

No new signals fired.

SDGR's lead widened by 2 AIQ points in the latest snapshot.

Deeper signal detail for each name lives on its own signals page — SDGR and TEM both carry a full feed there.

The central trade-off

SDGR (Schrödinger, Inc.): the stronger current systematic profile, led by quality and value.

TEM (Tempus AI, Inc.): the counter-case, on analyst expectations — but at materially higher volatility, 116.7% against 69.8%.

The AIQ Score and Wall Street therefore point in different directions on this pair.

Which one fits your objective

The same two names rank differently depending on what you are optimizing for. All six reads are shown at once — none of them is hidden behind a toggle.

Balanced

SDGR

SDGR on the overall AIQ Score, which weights Quality and Value most heavily.

Growth

TEM

TEM on combined revenue and EPS growth.

Value

SDGR

SDGR on the peer-relative Value factor, by 17 points.

Momentum

SDGR

SDGR on the Momentum factor, by 8 points.

Lower downside

SDGR

SDGR on Risk Resilience, by 15 points.

Analyst upside

TEM

TEM on implied upside to the consensus price target.

AIQ vs Wall Street

The model and the Street disagree here: AIQ favors SDGR, analyst targets favor TEM. That disagreement is the most useful thing on this page.

MeasureSDGRTEMNote
Implied upside to target-0.1%+14.7%TEM has more room
Target dispersion0%+44.3%Lower is tighter analyst agreement
ConsensusBuyBuyContext, not a primary driver
Analysts covering17Higher coverage generally improves confidence

The two are measuring different things. The AIQ Score reads current fundamentals, valuation, trend and risk; analyst targets price forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something already priced in — it is worth resolving before acting on either.

Analyst targets are expectations, not predictions. Dispersion matters as much as the midpoint.

AIQ Agreement Matrix

4 of 6 covered evidence groups favor SDGR. A wide gap backed by one group is a weaker case than a narrow gap backed by five.

Evidence groupFavorsReading
AIQ ScoreSDGR52 vs 36
FundamentalsEvenEPS growth 109.9% vs 104.3%; TTM ROE -16.4% vs -54.7%; gross margin 56.9% vs 64%; operating margin -59.2% vs -19.8%
ValuationSDGRValue 52 vs 35
TechnicalsSDGRPrice vs 50-day 8.7% vs 5.5%; vs 200-day 24.2% vs 4.3%
Risk ResilienceSDGRRisk Resilience 43 vs 28
Analyst expectationsTEMTarget upside -0.1% vs 14.7%

✓ agrees with the overall verdict · ✕ points the other way. Groups marked “not covered” lack data on one or both of SDGR and TEM and are excluded from the count.

AIQ Decision Stability

Competitive

The two are close enough that your objective, not the score, should decide.

  • The AIQ gap is wide at 16 points. (supports the conclusion holding)
  • The lead has been steady session to session. (supports the conclusion holding)
  • The leader is throwing conflicting signals. (argues the conclusion is provisional)

Stability combines the score gap, how broadly the evidence agrees, how steady the lead has been across daily snapshots, the current signal state on both names, and analyst dispersion on SDGR.

How the comparison changed

119 daily snapshots · May 4 Sep 10

SDGR lead: Stable — the AIQ differential has held near 16 points over 30 sessions.

May 4SDGR leads above the line · TEM leads belowSep 10
Today
SDGR +16
52 vs 36
7 sessions ago
SDGR +15
56 vs 41
30 sessions ago
SDGR +14
58 vs 44
90 sessions ago
SDGR +16
57 vs 41

The lead has not changed hands in this window.

AIQ Signal Divergence

Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.

SDGRConflicted

3 bullish / 1 bearish / 2 neutral, conflicted

  • Golden Cross Active bullish, trend, long horizon (15.61%)
  • Bollinger Band Squeeze neutral, volatility, short horizon
  • EMA Ribbon Expansion Bullish bullish, trend, medium horizon
TEMConflicted

1 bullish / 2 bearish / 1 neutral, conflicted

  • Death Cross Active bearish, trend, long horizon (0.71%)
  • EMA Ribbon Expansion Bullish bullish, trend, medium horizon
  • ATR Expansion - Breakout Mode neutral, volatility, short horizon (7.49%)

SDGR leads the comparison while carrying a conflicted signal state, which is one reason the stability rating is not higher.

Price vs model alignment

Whether the latest session's price move confirms what the model did over the same session, or contradicts it.

SDGRNo material change

Neither the price nor the AIQ Score moved enough in the latest session to confirm or contradict the other (price +1.17%, AIQ 0 points).

TEMDivergence

Price is up while the AIQ Score moved down 2 points over the same session — price and model disagree (price +0.46%, AIQ -2 points).

What would flip this result

A state, not a forecast. These are the specific, observable changes that would reverse the verdict — not a price prediction.

  1. 1TEM closes the Quality gap — currently 22 points behind, the largest single contributor to SDGR's edge.
  2. 2TEM's Death Cross Active resolves — a bearish trend rule currently active against it.
  3. 3SDGR's conflicting signal state resolves bearish — it currently carries 3 bullish and 1 bearish rules at once.
  4. 4A regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

The full evidence

Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.

Fundamentals

Split
MetricSDGRTEM
Revenue growth (YoY)0.5%9.9%
EPS growth (YoY)109.9%104.3%
Gross margin56.9%64%
Operating margin-59.2%-19.8%
Return on equity (TTM)-16.4%-54.7%
Debt to equity0.333.25

Performance

SDGR leads 4 of 6 windows
MetricSDGRTEM
1 week (5 sessions)-10%-5.2%
1 month (20 sessions)0.9%7.6%
3 months (63 sessions)32.9%18.7%
6 months (126 sessions)47.7%11.5%
Year to date5.1%-0.5%
1 year (252 sessions)-3.3%-26.8%

Technicals

SDGR has the stronger structure
MetricSDGRTEM
RSI (14)45.238.7
ADX (14)32.827.4
Price vs 50-day8.7%5.5%
Price vs 200-day24.2%4.3%
Volatility (1M, annualized)69.8%116.7%

Risk

SDGR is the more resilient
MetricSDGRTEM
Beta1.592.55
Sharpe ratio0.14-0.15
Sortino ratio0.23-0.3
Max drawdown-50.8%-59.8%
Current drawdown-16.5%-43.1%
Annualized volatility55.1%72.2%
Value at risk (95%)-5.3%-6%

Straight answers

Each answer is regenerated from the current snapshot, not written once and left to age.

Which is better, SDGR or TEM?

On the Algovestiq AIQ Score, SDGR is the stronger of the two as of Sep 11, 2026, scoring 52 against TEM's 36. The edge comes from quality and value. This is a systematic score, not a recommendation: it ranks the two on the same evidence, it does not know your holding period or tax position.

Is SDGR or TEM the better buy right now?

SDGR carries the stronger systematic profile as of Sep 11, 2026, and the comparison is rated Competitive — 4 of 6 covered evidence groups agree. A Competitive rating means the two are close enough that your objective, not the score, should decide.

Why does the AIQ Score favor SDGR over TEM?

The composite weights Quality, Value, Momentum and Risk Resilience. SDGR leads Quality by 22 points; SDGR leads Value by 17 points; SDGR leads Risk Resilience by 15 points. SDGR leads on all four AIQ factor dimensions. Value is itself one of those four, so the sweep is not explained by TEM simply being cheaper — it warrants extra scrutiny for unmodeled catalysts, forward expectations or event risk the factors do not capture.

Which has more analyst upside, SDGR or TEM?

Analyst price targets imply -0.1% upside for SDGR and +14.7% for TEM, so the Street currently favors TEM. That points the opposite way to the AIQ Score, which favors SDGR. The two are measuring different things: the model reads current fundamentals, valuation, trend and risk; the Street is pricing forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something the analysts have already priced — it is the single most useful row on this page to investigate. Analyst targets are expectations, not predictions, and dispersion matters as much as the midpoint.

Which is better value, SDGR or TEM?

SDGR is the better-valued of the two on the peer-relative Value factor. SDGR on the peer-relative Value factor, by 17 points. The Value factor reads valuation relative to sector peers and to the company's own fundamental quality, so it is not the same as simply having the lower multiple.

Which has stronger growth, SDGR or TEM?

TEM on combined revenue and EPS growth. Growth here is measured on reported revenue and earnings, not on forward estimates — it describes what the businesses have delivered, not what the Street expects next.

Which has stronger momentum, SDGR or TEM?

SDGR on the Momentum factor, by 8 points. Momentum is one of the four weighted factors in the AIQ composite. It has documented persistence over three- to twelve-month horizons, which makes it a timing input rather than a reason to hold something indefinitely.

Which is riskier, SDGR or TEM?

SDGR is the more resilient of the two, so the other name carries the higher downside risk. SDGR on Risk Resilience, by 15 points. Risk Resilience is a weighted factor in the composite; position sizing usually responds to it more usefully than the buy/avoid decision does.

Is SDGR more profitable than TEM?

The profitability evidence is mixed: gross margin 56.9% vs 64%; operating margin -59.2% vs -19.8%; ttm roe -16.4% vs -54.7%. SDGR leads on one measure and TEM on two measures, and there is no single profitability composite that resolves the split — which of the two reads as "more profitable" depends on whether you weight pricing power or operating leverage.

Is SDGR's lead over TEM getting stronger or weaker?

SDGR lead: Stable — the AIQ differential has held near 16 points over 30 sessions. This is measured from 119 daily comparison snapshots between 2026-05-04 and 2026-09-10. The lead has not changed hands in that window.

What would change the SDGR vs TEM verdict?

The result is a state, not a forecast, so it changes when the underlying evidence changes. Concretely: TEM closes the Quality gap — currently 22 points behind, the largest single contributor to SDGR's edge; TEM's Death Cross Active resolves — a bearish trend rule currently active against it; SDGR's conflicting signal state resolves bearish — it currently carries 3 bullish and 1 bearish rules at once; a regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

What do the current signals say about SDGR and TEM?

SDGR: 3 bullish / 1 bearish / 2 neutral, conflicted. TEM: 1 bullish / 2 bearish / 1 neutral, conflicted. A conflicted state means bullish and bearish rules are active on the same name at once — the technical evidence is not pointing one way, and a decision taken on it carries more timing risk. The most decision-relevant rule on SDGR is Golden Cross Active (bullish, long horizon). On TEM it is Death Cross Active (bearish, long horizon).

Compare SDGR and TEM with others

Continue your research

This page answers which of the two. These answer the questions on either side of it.

How this comparison is scored

The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.

The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.

How to use side-by-side comparison →

This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.