SRPT vs XNCR Stock Comparison

Compare SRPT and XNCR across AIQ Score, fundamentals, valuation, momentum, risk, analyst expectations and current market evidence.

Market data as of Sep 11, 2026 market close· AIQ score gap 10 points
SRPT
Healthcare
vs
XNCR
Healthcare
SRPT
Sarepta Therapeutics, Inc.
Leads
Price
$20.45
Day move
-0.34%
AIQ Score
55/100
Best edge
Value
Sector
Healthcare
XNCR
Xencor, Inc.
Price
$24.41
Day move
+0.62%
AIQ Score
45/100
Best edge
Risk Resilience
Sector
Healthcare

What is the main difference between SRPT and XNCR?

SRPT leads the current stock comparison as Sarepta Therapeutics, Inc., with the clearest separation coming from value and the broader AIQ evidence mix.

AlgovestIQ AIQ Comparison

Sarepta Therapeutics, Inc. vs Xencor, Inc.

Data as of Sep 11, 2026· market close· Healthcare· Coverage 66/66 fields· High confidence
AIQ VerdictFragileAIQ Comparison Conviction 5/10

SRPT leads

SRPT leads by 10 AIQ points, primarily on Value and Momentum, and the lead has widened from 6 points over 30 sessions. Wall Street currently favors XNCR on target upside.

Fragile: 3 of 6 evidence groups support SRPT, its lead is widening, and its current signal state is conflicted.

Evidence agreement: 3 of 6Comparison trend: Strengthening
SRPT

Sarepta Therapeutics, Inc.

Leads
AIQ Score
55/100
AIQ Edge Score
8/10
XNCR

Xencor, Inc.

AIQ Score
45/100
AIQ Edge Score
4/10

The Algovestiq AIQ Score currently favors SRPT over XNCR, 55 versus 45 as of Sep 11, 2026. SRPT's advantage is driven primarily by stronger value and momentum, while XNCR holds the stronger risk resilience profile. SRPT also shows the weaker technical structure relative to its 50-day moving average, though analyst target upside currently favors XNCR. 3 of 6 covered evidence groups favor SRPT today, and the comparison is rated Fragile on stability: only 3 of 6 covered evidence groups agree. SRPT lead: Strengthening — the AIQ differential moved from 6 to 10 points over 30 sessions.

Compare Sarepta Therapeutics, Inc. and Xencor, Inc. across the Algovestiq AIQ Score, valuation, quality, momentum, risk, technicals and analyst expectations.

Currently unavailable

Performance over time

Price-return comparison using available daily close history.

SRPT
-74.9%
XNCR
-27.0%

Total return comparison

Growth of $10,000

SRPT $2,507 · XNCR $7,301

Based on available close-price history. Distribution reinvestment is not added unless already reflected in the source series.

Compare SRPT and XNCR against another ticker

Open a multi-ticker workspace without changing this focused pair page.

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AIQ Factor Divergence

Where the two separate, on the four dimensions behind the AIQ Score. Bars read outward from a shared zero: further from the centre is a wider gap.

SRPT advantage
0
XNCR advantage
  • Value64 vs 34
    SRPT +30
  • Risk Resilience38 vs 55
    XNCR +17
  • Momentum66 vs 50
    SRPT +16
  • Quality46 vs 48
    Even

3 of 6 evidence groups favor SRPT. SRPT’s edge is concentrated in value and momentum; XNCR keeps a meaningful risk resilience edge.

What changed since the last close

Latest scored session 2026-09-10, compared against the prior scored session 2026-09-09.

SRPT-1 AIQ

Largest factor move: Momentum -5

No new signals fired.

XNCR-1 AIQ

Largest factor move: Momentum -1

New signals

  • Bollinger Band Squeeze neutral, volatility, short horizon

SRPT's lead was unchanged in the latest snapshot.

Deeper signal detail for each name lives on its own signals page — SRPT and XNCR both carry a full feed there.

The central trade-off

SRPT (Sarepta Therapeutics, Inc.): the stronger current systematic profile, led by value and momentum.

XNCR (Xencor, Inc.): the counter-case, on risk resilience, technicals, analyst expectations.

The AIQ Score and Wall Street therefore point in different directions on this pair.

Which one fits your objective

The same two names rank differently depending on what you are optimizing for. All six reads are shown at once — none of them is hidden behind a toggle.

Balanced

SRPT

SRPT on the overall AIQ Score, which weights Quality and Value most heavily.

Growth

XNCR

XNCR on combined revenue and EPS growth.

Value

SRPT

SRPT on the peer-relative Value factor, by 30 points.

Momentum

SRPT

SRPT on the Momentum factor, by 16 points.

Lower downside

XNCR

XNCR on Risk Resilience, by 17 points.

Analyst upside

XNCR

XNCR on implied upside to the consensus price target.

AIQ vs Wall Street

The model and the Street disagree here: AIQ favors SRPT, analyst targets favor XNCR. That disagreement is the most useful thing on this page.

MeasureSRPTXNCRNote
Implied upside to target+14.1%+40.3%XNCR has more room
Target dispersion+90%+75.9%Lower is tighter analyst agreement
ConsensusHoldBuyContext, not a primary driver
Analysts covering64Higher coverage generally improves confidence

The two are measuring different things. The AIQ Score reads current fundamentals, valuation, trend and risk; analyst targets price forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something already priced in — it is worth resolving before acting on either.

Analyst targets are expectations, not predictions. Dispersion matters as much as the midpoint.

AIQ Agreement Matrix

3 of 6 covered evidence groups favor SRPT. A wide gap backed by one group is a weaker case than a narrow gap backed by five.

Evidence groupFavorsReading
AIQ ScoreSRPT55 vs 45
FundamentalsSRPTon balancerevenue growth -45.1% vs 10.3%; EPS growth -101.6% vs 83%; TTM ROE -10% vs -28.7%; gross margin 58.6% vs 43.3%; operating margin -7.3% vs -205.8% — SRPT takes 3 of 5 decided legs, not all of them
ValuationSRPTValue 64 vs 34
TechnicalsXNCRPrice vs 50-day 10.9% vs 12.9%; vs 200-day 6.6% vs 58.8%
Risk ResilienceXNCRRisk Resilience 38 vs 55
Analyst expectationsXNCRTarget upside 14.1% vs 40.3%

✓ agrees with the overall verdict · ✕ points the other way. Groups marked “not covered” lack data on one or both of SRPT and XNCR and are excluded from the count.

AIQ Decision Stability

Fragile

The conclusion is sensitive to small changes. Treat the lead as provisional and watch the flip conditions below.

  • The AIQ gap is moderate at 10 points.
  • Only 3 of 6 covered evidence groups agree. (argues the conclusion is provisional)
  • The leader's advantage has been widening. (supports the conclusion holding)
  • The lead has been steady session to session. (supports the conclusion holding)
  • The leader is throwing conflicting signals. (argues the conclusion is provisional)
  • Analyst targets on the leader are widely dispersed. (argues the conclusion is provisional)

Stability combines the score gap, how broadly the evidence agrees, how steady the lead has been across daily snapshots, the current signal state on both names, and analyst dispersion on SRPT.

How the comparison changed

119 daily snapshots · May 4 Sep 10

SRPT lead: Strengthening — the AIQ differential moved from 6 to 10 points over 30 sessions.

May 4SRPT leads above the line · XNCR leads belowSep 10
Today
SRPT +10
55 vs 45
7 sessions ago
SRPT +8
58 vs 50
30 sessions ago
SRPT +6
59 vs 53
90 sessions ago
SRPT +6
59 vs 53

The lead changed hands 3 times in this window, most recently on Jul 17 when XNCR moved ahead of SRPT.

AIQ Signal Divergence

Only the signals that bear on the head-to-head. A conflicted name is carrying bullish and bearish rules at the same time — the technical evidence is not pointing one way.

SRPTConflicted

2 bullish / 1 bearish / 2 neutral, conflicted

  • Death Cross Active bearish, trend, long horizon (4.35%)
  • Bollinger Band Squeeze neutral, volatility, short horizon
  • EMA Ribbon Expansion Bullish bullish, trend, medium horizon
XNCRConflicted

3 bullish / 1 bearish / 2 neutral, conflicted

  • Golden Cross Active bullish, trend, long horizon (41.52%)
  • Bollinger Band Squeeze neutral, volatility, short horizon
  • EMA Ribbon Expansion Bullish bullish, trend, medium horizon

SRPT leads the comparison while carrying a conflicted signal state, which is one reason the stability rating is not higher.

Price vs model alignment

Whether the latest session's price move confirms what the model did over the same session, or contradicts it.

SRPTConfirmed weakness

Price and the AIQ Score both moved down over the latest session (price -0.34%, AIQ -1 points).

XNCRDivergence

Price is up while the AIQ Score moved down 1 points over the same session — price and model disagree (price +0.62%, AIQ -1 points).

What would flip this result

A state, not a forecast. These are the specific, observable changes that would reverse the verdict — not a price prediction.

  1. 1XNCR closes the Value gap — currently 30 points behind, the largest single contributor to SRPT's edge.
  2. 2XNCR's Bollinger Band Squeeze turns directional — it is neutral today and would confirm a change in trend.
  3. 3SRPT's conflicting signal state resolves bearish — it currently carries 2 bullish and 1 bearish rules at once.
  4. 4A regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

The full evidence

Every number behind the verdict. The leader is called above each group so you are not left to solve it from the table.

Fundamentals

SRPT leads on balance
MetricSRPTXNCR
Revenue growth (YoY)-45.1%10.3%
EPS growth (YoY)-101.6%83%
Gross margin58.6%43.3%
Operating margin-7.3%-205.8%
Return on equity (TTM)-10%-28.7%
Debt to equity0.680.13

Performance

XNCR leads 5 of 6 windows
MetricSRPTXNCR
1 week (5 sessions)-11.6%-9.8%
1 month (20 sessions)11.6%4.7%
3 months (63 sessions)35.8%105.1%
6 months (126 sessions)16.8%101.5%
Year to date-4.6%58.5%
1 year (252 sessions)16.6%188.5%

Technicals

XNCR has the stronger structure
MetricSRPTXNCR
RSI (14)55.238.5
ADX (14)3252
Price vs 50-day10.9%12.9%
Price vs 200-day6.6%58.8%
Volatility (1M, annualized)79.3%71.1%

Risk

XNCR is the more resilient
MetricSRPTXNCR
Beta2.11.24
Sharpe ratio0.551.88
Sortino ratio0.763.32
Max drawdown-39.2%-42.6%
Current drawdown-16.1%-17.2%
Annualized volatility81.3%67.2%
Value at risk (95%)-6.6%-5.7%

Straight answers

Each answer is regenerated from the current snapshot, not written once and left to age.

Which is better, SRPT or XNCR?

On the Algovestiq AIQ Score, SRPT is the stronger of the two as of Sep 11, 2026, scoring 55 against XNCR's 45. The edge comes from value and momentum. XNCR is not without a case — it holds the better risk resilience profile, which matters more if that is the objective you are optimizing for. This is a systematic score, not a recommendation: it ranks the two on the same evidence, it does not know your holding period or tax position.

Is SRPT or XNCR the better buy right now?

SRPT carries the stronger systematic profile as of Sep 11, 2026, and the comparison is rated Fragile — 3 of 6 covered evidence groups agree. A Fragile rating means the conclusion is sensitive: only 3 of 6 covered evidence groups agree. Treat the lead as provisional.

Why does the AIQ Score favor SRPT over XNCR?

The composite weights Quality, Value, Momentum and Risk Resilience. SRPT leads Value by 30 points; XNCR leads Risk Resilience by 17 points; SRPT leads Momentum by 16 points. Where the two split, the factor with the larger weight carries the result.

Which has more analyst upside, SRPT or XNCR?

Analyst price targets imply +14.1% upside for SRPT and +40.3% for XNCR, so the Street currently favors XNCR. That points the opposite way to the AIQ Score, which favors SRPT. The two are measuring different things: the model reads current fundamentals, valuation, trend and risk; the Street is pricing forward expectations. A divergence of this kind is either a contrarian opportunity or a sign the model is missing something the analysts have already priced — it is the single most useful row on this page to investigate. Analyst targets are expectations, not predictions, and dispersion matters as much as the midpoint.

Which is better value, SRPT or XNCR?

SRPT is the better-valued of the two on the peer-relative Value factor. SRPT on the peer-relative Value factor, by 30 points. The Value factor reads valuation relative to sector peers and to the company's own fundamental quality, so it is not the same as simply having the lower multiple.

Which has stronger growth, SRPT or XNCR?

XNCR on combined revenue and EPS growth. Growth here is measured on reported revenue and earnings, not on forward estimates — it describes what the businesses have delivered, not what the Street expects next.

Which has stronger momentum, SRPT or XNCR?

SRPT on the Momentum factor, by 16 points. Momentum is one of the four weighted factors in the AIQ composite. It has documented persistence over three- to twelve-month horizons, which makes it a timing input rather than a reason to hold something indefinitely.

Which is riskier, SRPT or XNCR?

XNCR is the more resilient of the two, so the other name carries the higher downside risk. XNCR on Risk Resilience, by 17 points. Risk Resilience is a weighted factor in the composite; position sizing usually responds to it more usefully than the buy/avoid decision does.

Is SRPT more profitable than XNCR?

SRPT leads on the comparable margin measures — gross margin 58.6% vs 43.3%; operating margin -7.3% vs -205.8%; ttm roe -10% vs -28.7%.

Is SRPT's lead over XNCR getting stronger or weaker?

SRPT lead: Strengthening — the AIQ differential moved from 6 to 10 points over 30 sessions. This is measured from 119 daily comparison snapshots between 2026-05-04 and 2026-09-10. The lead has changed hands 3 times in that window, most recently on 2026-07-17, when XNCR moved ahead of SRPT.

What would change the SRPT vs XNCR verdict?

The result is a state, not a forecast, so it changes when the underlying evidence changes. Concretely: XNCR closes the Value gap — currently 30 points behind, the largest single contributor to SRPT's edge; XNCR's Bollinger Band Squeeze turns directional — it is neutral today and would confirm a change in trend; SRPT's conflicting signal state resolves bearish — it currently carries 2 bullish and 1 bearish rules at once; a regime shift changes factor weighting — Quality and Value carry the heaviest weights in the composite, so a rotation toward either would move the result most.

What do the current signals say about SRPT and XNCR?

SRPT: 2 bullish / 1 bearish / 2 neutral, conflicted. XNCR: 3 bullish / 1 bearish / 2 neutral, conflicted. A conflicted state means bullish and bearish rules are active on the same name at once — the technical evidence is not pointing one way, and a decision taken on it carries more timing risk. The most decision-relevant rule on SRPT is Death Cross Active (bearish, long horizon). On XNCR it is Golden Cross Active (bullish, long horizon).

Compare SRPT and XNCR with others

Continue your research

This page answers which of the two. These answer the questions on either side of it.

How this comparison is scored

The Algovestiq AIQ Score composites four factors — Quality, Value, Momentum and Risk, each carrying a fixed weight. Sentiment is reported separately as SentimentPulse and is not folded into the composite. Scores refresh every trading day, and this page regenerates from the latest snapshot rather than being written once.

The verdict names a leader, states how broadly six independent evidence groups agree, and rates how durable that conclusion is given the score gap, its recent trajectory and the current signal state on both names.

How to use side-by-side comparison →

This comparison is informational and educational, not investment advice. AIQ scores update daily; re-check after earnings, guidance or macro data that materially changes either name’s factor profile.